HIGH-RISK PROSTATE CANCER
Clinical trials for HIGH-RISK PROSTATE CANCER explained in plain language.
Never miss a new study
Get alerted when new HIGH-RISK PROSTATE CANCER trials appear
Sign up with your email to follow new studies for HIGH-RISK PROSTATE CANCER, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
Triple-Drug attack before surgery aims to wipe out High-Risk prostate cancer
Disease control Recruiting nowThis study tests whether giving a mix of hormone therapy (ADT), a targeted drug (darolutamide), and an immunotherapy (pembrolizumab) before prostate removal surgery, followed by more immunotherapy after surgery, can reduce or eliminate cancer in high-risk prostate cancer patients…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: PHASE2 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
-
New radiation approach aims to improve prostate cancer outcomes
Disease control Recruiting nowThis study tests a new type of radiation therapy for men with high-risk prostate cancer that has not spread. The new approach uses advanced imaging to deliver a higher dose of radiation directly to the main tumor while also treating the surrounding pelvic area. The goal is to see…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: NA • Sponsor: Center Eugene Marquis • Aim: Disease control
Last updated May 16, 2026 23:36 UTC
-
Could a Pre-Surgery epigenetic boost help fight prostate cancer?
Disease control Recruiting nowThis early-stage study is testing whether giving an epigenetic therapy before prostate removal surgery can make the tumor more visible to the immune system. About 20 men with high-risk prostate cancer will receive the drug before their scheduled prostatectomy. The main goals are …
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: EARLY_PHASE1 • Sponsor: Edwin Posadas, MD • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
-
New drug cocktail aims to wipe out tough prostate tumors before surgery
Disease control Recruiting nowThis study is for men with high-risk prostate cancer that has a specific genetic change (PTEN loss). Before surgery to remove the prostate, participants will take a combination of three drugs: capivasertib, abiraterone, and leuprolide. The goal is to see if this treatment can shr…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
-
New hope for High-Risk prostate cancer: which targeted radiation works best?
Disease control Recruiting nowThis early-stage study tests two types of targeted radiation therapy (177Lu-PSMA-617 and 225Ac-PSMA-617) in 45 men with high-risk prostate cancer who are scheduled for prostate removal surgery. The goal is to see which therapy delivers more radiation to the tumor and how it affec…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: PHASE1 • Sponsor: Thomas Hope • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
-
New radioactive drug shows promise before prostate removal in early trial
Disease control Recruiting nowThis study tests a new radioactive drug (Tb-PSMA) given before surgery to remove the prostate in men with high-risk prostate cancer. The goal is to see if it is safe and helps improve surgical outcomes. About 20 men will take part, and the drug has shown promise in advanced cance…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: PHASE1, PHASE2 • Sponsor: Rabin Medical Center • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
-
New scan cuts radiation for prostate cancer patients
Diagnosis Recruiting nowThis study tests a new way to scan men with high-risk prostate cancer using a special PET/CT tracer. The approach adds a delayed pelvic image without a second CT scan, reducing radiation exposure and saving time. Researchers will check if the image quality stays good enough to fi…
Matched conditions: HIGH-RISK PROSTATE CANCER
Phase: NA • Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Diagnosis
Last updated May 16, 2026 23:49 UTC
-
New scan method could revolutionize prostate cancer monitoring
Knowledge-focused Recruiting nowThis study looks at whether a special type of PET scan (PSMA PET) can better track how well prostate cancer treatment is working. It involves 110 men with newly diagnosed, aggressive prostate cancer. They will get a PSMA PET scan before treatment and another one after treatment t…
Matched conditions: HIGH-RISK PROSTATE CANCER
Sponsor: Xijing Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
-
Can a genetic test help men with BRCA mutations make smarter screening choices?
Knowledge-focused Recruiting nowThis study looks at how men aged 45-70 with BRCA1/2 gene mutations (which raise prostate cancer risk) react to additional genetic risk testing. Researchers want to see if this extra information changes their decisions about prostate cancer screening. The goal is to understand how…
Matched conditions: HIGH-RISK PROSTATE CANCER
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC