New imaging technique aims to sharpen prostate cancer radiation

NCT ID NCT07393867

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is for men with intermediate- or high-risk prostate cancer who will receive hormone therapy and radiation. Researchers want to see if using a special PET scan (PSMA PET) during hormone therapy can help doctors better target remaining cancer with radiation while avoiding healthy tissue. Participants will get standard treatments plus three imaging scans over six months. The goal is to make radiation more precise and reduce side effects in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PSMA PET/CT imaging and androgen deprivation therapy (ADT) with or without bicalutamide

What this could lead to

If successful, this could lead to more precise radiation treatment for prostate cancer, potentially reducing side effects while maintaining effectiveness.

What could go wrong

This is a small, early-phase study with only 23 participants, so results may not apply to all patients. The imaging technique may not improve outcomes as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center

    RECRUITING

    Milford, Massachusetts, 01757, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber/Brigham and Women's Cancer Center in Clinical Affiliation with South Shore Hospital

    RECRUITING

    Weymouth, Massachusetts, 02190, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••