PROSTATE CANCER (DIAGNOSIS)

This early-stage study tests two types of targeted radiation therapy (177Lu-PSMA-617 and 225Ac-PSMA-617) in 45 men with high-risk prostate cancer who are scheduled for prostate removal surgery. The goal is to see which therapy delivers more radiation to the tumor and how it affec…

This study tests if a daily pill (abiraterone with prednisone) can lower testosterone enough to control prostate cancer, without using standard hormone-blocking injections. About 60 men with advanced prostate cancer who need stronger hormone therapy will take the pill and be moni…

This study is testing a new blood test that looks at proteins in platelets (a type of blood cell) to see if it can better detect prostate cancer and tell how serious it is. Researchers at Duke University will enroll 300 men who are already being checked for prostate cancer. The g…

This early-stage trial tests a new robot called ProBot that helps doctors perform prostate biopsies with greater precision. The robot uses a special ultrasound probe and aims to reduce pain and improve accuracy when taking tissue samples. About 60 men aged 40-75 with high-risk fe…

This study is developing a blood test that looks at genetic material from tiny particles (exosomes) to predict if prostate cancer has spread to the bones. Researchers will enroll 1,000 men with newly diagnosed prostate cancer to see if the test can accurately rule out bone metast…

This study is testing new types of MRI scans to see if they can more accurately find and grade prostate cancer without using a contrast dye. About 300 men with suspected prostate cancer will get both standard and new MRI scans. The results will be checked against biopsy or surger…

This study tests a new way to decide who needs a prostate biopsy. Instead of relying only on MRI, it adds a blood test called Prostate Health Index (PHI) to better tell which men have dangerous prostate cancer. The goal is to safely skip biopsies in men who don't need them, reduc…

This study aims to see if a new type of PET/CT scan that targets a protein called ACP3 can find prostate cancer tumors as well as or better than current scans. About 100 adults with newly diagnosed or recurring prostate cancer will receive both the new ACP3 scan and standard PSMA…

This study tests whether combining PSMA PET scans with machine learning can accurately determine how aggressive a prostate cancer is, without needing repeated invasive biopsies. Researchers will scan 220 men with suspected or known prostate cancer and use AI to predict the cancer…

This study compares two ways of taking prostate biopsies to see which finds dangerous cancers more accurately while avoiding unnecessary detection of harmless ones. About 592 men with a suspicious MRI finding will get either targeted plus perilesional biopsies or a combination th…

This study tests a 12-week prehabilitation program for 20 prostate cancer patients about to start hormone therapy and radiation. The program includes exercise training and a 4-day residential course with education and activities. The goal is to see if patients and their families …

This study tests a digital exercise program designed to help prostate cancer patients on hormone therapy stick with physical activity. Side effects like weight gain, muscle loss, and fatigue are common, and exercise can help, but many patients struggle to keep it up. The trial wi…

This study follows 500 men who had their prostate removed for cancer. Researchers check PSA levels soon after surgery to see if they can predict if the cancer will come back or spread. No new treatments are given—just standard care and observation.

This study looks at how well a virtual oncology program works for veterans with lung, colorectal, prostate, or breast cancer. About 1,800 veterans will take part to see if using video or phone visits improves their care and lowers costs. The goal is to learn how to make cancer ca…

This study looks at how the immune system changes in 200 prostate cancer patients before, during, and after brachytherapy (internal radiation). Researchers will analyze blood and tissue samples to understand immune responses and track long-term outcomes like cancer recurrence and…

This study follows men who had a prostate MRI showing suspicious spots but no significant cancer on their first biopsy. Researchers will repeat MRIs and biopsies over time to see if changes in those spots can predict future cancer. The goal is to better understand which men need …

This study looks at whether adding a special scan called PSMA PET to the usual MRI can help find prostate cancer that comes back after focal therapy (a treatment that targets only the tumor). About 62 men who have had focal therapy will get both scans. The goal is to see if the P…

This study aims to understand the real-world picture of prostate cancer in Algeria. Researchers will observe 2,000 patients to learn about their backgrounds, how they were diagnosed, and what treatments they receive. The goal is to gather information to help improve future care, …