Hidden vein clot cleanup may prevent chronic leg pain

This study tests whether removing a blood clot from a specific thigh vein (the profunda femoris vein) during standard treatment for a large leg vein clot can prevent long-term complications like pain and swelling. About 140 adults with recent leg clots will be randomly assigned to get the extra clot removal or standard care alone. The goal is to see if this extra step reduces the chance of developing post-thrombotic syndrome.