Timing of blood thinners after childbirth bleeding may prevent clots without causing more harm
NCT ID NCT07689136
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This study examines the best time to start blood thinners in women who have had severe bleeding after childbirth. Researchers are looking at whether starting blood thinners within 24 hours or later affects the risk of blood clots or further bleeding. The goal is to find a balance that protects mothers from dangerous clots without increasing bleeding complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low Molecular Weight Heparin (LMWH) or Unfractionated Heparin (UFH)
- What this could lead to
- If successful, this could help doctors decide the safest time to start blood thinners after severe postpartum bleeding, reducing the risk of dangerous blood clots without increasing bleeding.
- What could go wrong
- This is a retrospective study, meaning it looks back at past records, so it cannot prove cause and effect. The results may not apply to all hospitals or patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
236 people
The number who actually took part.
- Started
-
Mar 2025
- Finished
-
Mar 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women with postpartum hemorrhage managed at the Maternity and Neonatology Center of Tunis, who received pharmacologic thromboprophylaxis during the postpartum period and met the study eligibility criteria.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women who delivered vaginally or by cesarean section in the obstetrics and gynecology departments of Maternity and Neonatology Center of Tunis. * Diagnosed with postpartum hemorrhage. * subsequently admitted to the intensive care unit (ICU). Exclusion Criteria: * Women with recurrent hemorrhage related to a surgical complication (e.g., splenic decapsulation during dry mopping, suture dehiscence, vascular injury). * Women who underwent radiological arterial embolization. * Medical records with incomplete or non-exploitable data.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Center of Maternity and Neonatology of Tunis (CMNT)
Tunis, 1007, Tunisia
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