POSTPARTUM HEMORRHAGE

This study tests whether draining the umbilical cord after delivery can lower the risk of severe bleeding (postpartum hemorrhage) in new mothers. Researchers will compare blood loss, hemoglobin drops, and need for extra treatments between 400 women who receive cord drainage and t…

This study tests a set of simple, proven steps (called the 'Rule of THUMB') to help doctors better prevent, spot, and treat severe bleeding during and after C-sections. About 2,400 women having C-sections in African hospitals will take part. The goal is to see if this care plan s…

This study looks for the smallest effective dose of oxytocin to keep the uterus contracted after a C-section in women who have been in labor. Oxytocin is a drug that helps prevent heavy bleeding after delivery. About 40 women will take part, and the dose each woman gets will depe…

This study tests whether giving a clotting protein called factor XIII early can reduce blood loss in women with heavy bleeding after vaginal delivery. About 988 women in Switzerland will take part. If bleeding continues past a certain point, half receive the factor plus standard …

This study tests a device called AAJT-S that temporarily squeezes the main belly artery to stop severe bleeding after childbirth when standard treatments don't work. About 20 women with heavy bleeding will have the device placed on their abdomen and inflated for up to 5 minutes. …

This study tests a device called KOKO to safely stop heavy bleeding after childbirth. About 72 women who have abnormal bleeding or hemorrhage within 24 hours of delivery will use the device. The goal is to control bleeding and avoid the need for extra procedures or surgery.

This study looks at a new rapid test that measures a key blood clotting protein (fibrinogen) right at the bedside for women with severe bleeding after childbirth. The goal is to see if this quick test gives the same results as the standard lab test, which takes longer. If accurat…

This study tests if the drug carbetocin works better than standard oxytocin to prevent heavy bleeding after delivering twins. Heavy bleeding is more common with twin births and can cause serious health problems. About 120 pregnant women with twins will be randomly assigned to rec…

This study compares a serious video game to traditional teaching for nursing students learning how to handle postpartum hemorrhage (heavy bleeding after childbirth). About 70 third-year nursing students will be split into two groups: one gets the game-based training plus standard…

This study looks at how three common blood pressure drugs (ephedrine, phenylepinephrine, and norepinephrine) affect the ability of the uterus to contract after a C-section in women with type 2 or gestational diabetes. Researchers will take small samples of uterine tissue during t…

This study looks at whether opening the clamp on the umbilical cord after cutting it (called placental cord drainage) can shorten the time it takes for the placenta to come out and reduce blood loss after birth. About 80 low-risk pregnant women having a normal vaginal delivery wi…

This study uses tiny samples of uterine tissue from women having a planned C-section to test which backup drug works best to contract the uterus after the standard drug carbetocin. The goal is to find the most effective treatment to prevent severe bleeding after childbirth. The s…

This study reviews medical records of 648 women who had heavy bleeding after a C-section to see how often the drug tranexamic acid (TXA) was given over the years. TXA can reduce deaths from bleeding, and the study aims to understand if its use has increased and how it affects out…