POSTPARTUM HEMORRHAGE

This trial tests two common ways to remove the placenta during a cesarean delivery — manual removal or controlled cord traction — and whether a one-minute uterine massage after closing the incision helps prevent postpartum hemorrhage. The study includes 361 healthy women with a f…

This large study tested whether giving tranexamic acid right after a cesarean delivery can prevent postpartum hemorrhage, or dangerous heavy bleeding. Over 4,500 women participated across multiple hospitals. The drug was given as a single injection after the umbilical cord was cl…

This completed phase 3 trial tested whether adding tranexamic acid to recombinant von Willebrand factor (rVWF) reduces postpartum hemorrhage better than rVWF alone in 20 pregnant women with von Willebrand disease. Participants received either the combination or rVWF alone at deli…

This study tested two medications, methylergonovine and carboprost, to treat heavy bleeding after a C-section when the first drug (oxytocin) doesn't work. 100 women with postpartum hemorrhage due to a relaxed uterus were randomly assigned to one drug. Doctors measured how well th…

This study tested a new rapid bedside device (qLabs®FIB) that measures a key blood clotting protein called fibrinogen in women with severe bleeding after childbirth. The goal was to see if the quick test gives results as accurate as the standard lab test, which takes longer. 70 w…

This trial compares two medications—misoprostol (a pill placed under the tongue) and tranexamic acid (given through an IV)—to see which is more effective at preventing postpartum hemorrhage, or heavy bleeding, after a cesarean delivery. The study includes women aged 18-45 having …

This completed trial studied 200 first-time mothers having a normal vaginal delivery to find the best time to give carbetocin, a drug that prevents severe bleeding after childbirth. Researchers compared giving the drug at different times to see which reduced bleeding, side effect…

This study looks at how quickly and effectively oral calcium is absorbed into the blood of pregnant women during labor. Participants receive a single dose of calcium carbonate (like Tums) or calcium citrate, and blood calcium levels are tracked over four hours. The goal is to und…

This study investigates whether women who experience heavy bleeding (postpartum hemorrhage) after childbirth are more likely to develop depression, anxiety, or stress in the following year. Researchers will follow over 1,200 women who had a hemorrhage and compare them to those wh…

This study compares three devices that measure how well blood clots — ClotPro, ROTEM, and TEG — in patients undergoing liver surgery, neurosurgery, or cesarean section. The goal is to see how closely the results from these devices agree with each other. The findings may help doct…

This study examines the best time to start blood thinners in women who have had severe bleeding after childbirth. Researchers are looking at whether starting blood thinners within 24 hours or later affects the risk of blood clots or further bleeding. The goal is to find a balance…

This study tests whether a serious game can improve nursing students' knowledge and confidence in managing postpartum hemorrhage (severe bleeding after childbirth). Seventy third-year nursing students will be split into two groups: one gets traditional training plus the game, the…

This study looked at whether simulation-based education helps midwifery students learn to manage postpartum hemorrhage (heavy bleeding after childbirth). Forty-five third-year students were split into two groups: both got traditional lectures, but one group also practiced with a …

This study looked at how ketorolac, a non-steroidal anti-inflammatory drug (NSAID) used for pain after cesarean delivery, affects platelet function and blood clotting. Researchers measured clotting in 40 women undergoing scheduled C-sections using special blood tests. The goal wa…

This study examined how the drug tranexamic acid (TXA) affects blood clotting in women having planned C-sections. Researchers measured clot breakdown times in 34 participants to see if TXA could help prevent heavy bleeding after delivery. The goal was to better understand how TXA…

This study tested a device called Sonoclot to quickly measure blood clotting in 90 women who had severe bleeding within 24 hours after giving birth. The goal was to see if this point-of-care test could help doctors spot clotting problems faster and improve treatment. The study is…

This study reviewed the medical records of 649 women who had heavy bleeding (at least 1 liter) after a C-section. Researchers looked at how many needed blood transfusions, intensive care, or other treatments. The goal was to better understand what happens to these patients, not t…

This completed study looked at 1,000 women with autoimmune diseases (like lupus) who had a C-section. Researchers wanted to find out how many had severe bleeding (postpartum hemorrhage) and what factors increased that risk. By analyzing medical records, they hope to identify high…

This study looked at whether an Obstetric Comorbidity Index can predict severe health problems in women who had a C-section and experienced heavy bleeding. Researchers reviewed the records of 583 patients to see how well the index identified those at highest risk. The goal is to …