Which drug stops Post-Birth bleeding best? new trial has answers
NCT ID NCT03584854
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two medications, methylergonovine and carboprost, to treat heavy bleeding after a C-section when the first drug (oxytocin) doesn't work. 100 women with postpartum hemorrhage due to a relaxed uterus were randomly assigned to one drug. Doctors measured how well the uterus tightened up. The goal is to find which drug works better to stop dangerous bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methylergonovine and carboprost
What this could lead to
If one drug works better, it could become the preferred second-line treatment for severe bleeding after childbirth, improving outcomes for mothers.
What could go wrong
This is a small, completed trial with only 100 participants, so results may not apply to all women. The drugs also have side effects like high blood pressure or breathing problems.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States