Heart valve fix may heal scarred muscle, small study hints
NCT ID NCT07335900
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether replacing a narrowed heart valve (TAVI) can reverse damage to the heart muscle in people with severe aortic stenosis. Researchers will use special PET scans to measure scarring and remodeling in the heart before and 6 months after the procedure. The goal is to understand if relieving the blockage helps the heart heal and work better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter Aortic Valve Implantation (TAVI) procedure
What this could lead to
If successful, this could show that TAVI not only fixes the valve but also helps reverse heart muscle scarring and improve heart function.
What could go wrong
This is a small, early-stage imaging study (25 people) with no control group for the procedure. It measures changes in scans, not long-term health outcomes, so results may not lead to direct treatment changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Renji Hospital,Shanghai
RECRUITINGShanghai, 201203, China
Contact Phone: •••-•••-•••• Email: •••••@•••••