Renji Hospital

This study looks at how well minimally invasive procedures (like angioplasty and stents) work for people with severe blockages in the leg arteries. Researchers will track 1000 patients to see if these treatments restore blood flow, keep arteries open, and reduce the need for repe…

This study tests two drugs, fruquintinib and serplulimab, as a first treatment for people with a rare and hard-to-treat kidney cancer that has spread or cannot be removed. The goal is to see if the combination can shrink tumors or slow the disease. About 39 adults will take part,…

This early-stage study tests a single dose of YOLT-202 in 18 adults with Alpha-1 antitrypsin deficiency (AATD), a genetic condition that can damage the lungs and liver. The main goal is to check if the drug is safe and to find the best dose. Participants must stop their usual the…

This study tests whether adding an experimental drug (VIC-1911) to a standard targeted therapy (lenvatinib) can safely shrink tumors and slow disease progression in people with advanced liver cancer. About 12 adults aged 18-75 with stage C liver cancer and good liver function wil…

This study tests whether adding the targeted drug pyrotinib to standard chemotherapy and trastuzumab before surgery can completely eliminate tumors in women with early-stage HER2-positive breast cancer. About 53 women with stage II to III breast cancer will receive the combinatio…

This study compares two types of brain surgery for people with a severe head injury that causes a blood clot (epidural hematoma) and brain herniation (when brain tissue is pushed out of place). The two surgeries are decompressive craniectomy (removing part of the skull to relieve…

This study aims to create computer models that predict how long patients with advanced pancreatic cancer might live and how well they respond to chemotherapy. Researchers will analyze medical images, tissue samples, and genetic data from 100 participants. The goal is to help doct…