Muscle loss in kidney disease: could a simple supplement turn the tide?

NCT ID NCT06329622

Recruiting now Disease control Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether Ketosteril, a keto acid supplement taken with a low-protein diet, can improve muscle mass and strength in people with chronic kidney disease (CKD) stages 3-4 who also have sarcopenia (muscle wasting). The study compares the supplement plus diet against diet alone over six months. The goal is to see if Ketosteril can reverse muscle loss without putting extra strain on the kidneys.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketosteril (a keto acid supplement) plus a low-protein diet
What this could lead to: If it works, this could offer a way to treat muscle wasting in kidney disease patients without overloading the kidneys.
What could go wrong: This is a small, early-phase trial, so results may not apply broadly. Ketosteril may not improve muscle mass or could cause side effects like electrolyte imbalances.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE SARCOPENIA

Contacts and locations

Locations

Huashan hospital, Fudan university
RECRUITING

Shanghai, 200040, China

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