Aging kidneys under the microscope: could a simple test predict failure?

NCT ID NCT07765134

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This study looks at thousands of Chinese adults aged 60 and older to understand how kidney function changes with age. Researchers are examining a range of blood and urine markers to see which ones best predict kidney failure, heart problems, and death. They are also testing different ways to estimate kidney function and building a model that could give early warning of decline. The goal is to help doctors spot at-risk individuals sooner, potentially preventing or delaying serious kidney disease.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to a practical early-warning system that helps doctors identify older adults at high risk of kidney failure, potentially enabling earlier interventions to prevent or delay serious complications.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The early-warning model is developed and validated internally, so it may not work as well in other populations or settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Huashan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 200040, China

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