KIDNEY FAILURE

This early-stage study is testing a new combination treatment designed to help the body accept a donated kidney without needing lifelong anti-rejection drugs. The treatment involves a special bone marrow infusion from the kidney donor, along with medications and low-dose radiatio…

This early-stage study is testing a new cell therapy for people who have been waiting over a year for a kidney transplant and have immune systems that would reject almost any donor kidney. Researchers will collect a patient's own immune cells, modify them in a lab to target antib…

This study is testing whether a special high-protein egg white pudding can help people with kidney failure who are on dialysis. Researchers want to see if this pudding is a practical supplement that can improve nutrition and measures of strength and frailty. Participants will rec…

This study is testing a new type of artificial blood vessel, called the InnAVasc graft, for people with kidney failure who need dialysis. The goal is to see if this graft is safe and stays open long enough to be a reliable access point for dialysis treatments. Researchers will fo…

This international study aims to find the best way to start patients on home-based peritoneal dialysis (PD) for kidney failure. It will compare the standard full-dose treatment against a new, gradual approach that starts with a lower dose. The goal is to see if the gradual start …

This study is testing whether a new organ preservation solution called Custodiol-N works as well as the current standard solution during kidney, liver, and pancreas transplants. Researchers will compare how well the transplanted organs function in 362 patients over 90 days after …

This study is testing if a drug called empagliflozin, usually used for diabetes, can help raise low sodium levels in the blood. It will involve 172 hospitalized patients whose low sodium is linked to conditions like heart failure, liver disease, or a hormone imbalance (SIADH). Pa…

This study compares two different ultrasound-guided nerve block techniques to see which provides better pain relief after laparoscopic kidney removal surgery. Researchers will measure how much opioid pain medication patients need in the first 24 hours after surgery and track thei…

This study aims to understand how variations in a specific gene called APOL1 affect the long-term success of kidney transplants and the health of living kidney donors. It will enroll 5,000 participants, focusing on people of recent African ancestry who are more likely to have the…

This study aims to check the safety of the drug maribavir in adults who have had an organ or stem cell transplant, have a difficult-to-treat cytomegalovirus (CMV) infection, and also have severe kidney disease or kidney failure. Researchers will look at the existing medical recor…