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Could less dialysis at first be better? new trial aims to find out

NCT ID NCT06642597

Symptom relief Sponsor: The University of Queensland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether starting peritoneal dialysis (a home-based treatment for kidney failure) at a low dose and gradually increasing it can improve patients' quality of life compared to the standard full-dose approach. About 224 adults new to dialysis will take part. The goal is to see if a slower start reduces symptoms and preserves remaining kidney function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 224 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adults (≥18 years) commencing PD as their first dialysis therapy (and been on dialysis for \<1 month) * able to give informed consent Exclusion Criteria: * urine output \<0.5L/day * previous kidney transplant * unlikely to be on dialysis for ≥1 year. * known or planned pregnancy during the trial

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Conditions

The condition(s) this trial relates to.

kidney disorder kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney failure Peritoneal dialysis (PD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Banphaeo General Hospital

    RECRUITING

    Ban Phaeo, Changwat Samut Sakhon, 74120, Thailand

  • Blacktown

    RECRUITING

    Blacktown, New South Wales, 2148, Australia

  • Eastern Health

    RECRUITING

    Box Hill, Victoria, 3218, Australia

  • Hallym University Sacred Heart Hospital

    RECRUITING

    Chuncheon, Gangwon-do, 14068, South Korea

  • King Chulalongkorn Memorial Hospital

    RECRUITING

    Bangkok, Pathum Wan, 10330, Thailand

  • Kyungpook National University

    RECRUITING

    Daegu, South Korea

  • Princess Alexandra Hospital

    NOT_YET_RECRUITING

    Brisbane, Queensland, 4102, Australia

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, Xitun District, 1650, Taiwan

  • Waitemata

    RECRUITING

    Auckland, 0610, New Zealand

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