Engineered immune cells could unlock kidney transplants for 'Impossible-to-Match' patients
NCT ID NCT06056102
First seen Jan 08, 2026 · Last updated May 12, 2026 · Updated 19 times
Summary
This study tests a new approach using a patient's own modified immune cells (CAR T cells) to lower the risk of rejecting a donated kidney. It is for people with kidney failure who have been on the transplant waiting list for at least a year and have a very high chance of rejecting most donor kidneys. The goal is to see if this treatment is safe and can reduce the immune system's attack on donor kidneys, potentially making a transplant possible.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital: Transplantation (Site #: 71107)
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NYU Langone Health (Site #: 71177)
RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania Medical Center (Site #: 71111)
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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