Can amino acid supplements help reverse muscle wasting in liver disease patients?
NCT ID NCT07281846
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding branched-chain amino acid (BCAA) supplements to a standard liver procedure (TIPS) can help reverse muscle loss (sarcopenia) in people with cirrhosis and high blood pressure in the liver. About 164 patients will be randomly assigned to receive either BCAA supplements or a placebo for 3 months after TIPS. Researchers will measure changes in muscle mass and physical function over 6 months to see if the supplements make a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- branched-chain amino acid (BCAA) supplements
- What this could lead to
- If successful, this could show that adding BCAA supplements to TIPS helps reverse muscle loss and improve physical function in cirrhosis patients.
- What could go wrong
- This is a relatively small, early-stage trial (164 participants) and results may not apply to all patients. BCAA supplements may not significantly improve outcomes or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, China
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