Union Hospital, Tongji Medical College, Huazhong University Of Science And Technology

This study is investigating whether a standard medical procedure called TIPS, used to treat complications of advanced liver scarring (cirrhosis), can help the liver partially heal itself—a state called 'recompensation.' Researchers will follow 250 patients with cirrhosis who rece…

This is an early-stage study testing a new cell therapy called EVM18001 for people with severe, hard-to-treat autoimmune diseases: lupus, scleroderma, and myasthenia gravis. The main goal is to check if the treatment is safe and to find the right dose. Researchers will also look …

This study is testing whether sorbitol, a common sugar alcohol, can improve the effectiveness of standard chemotherapy and immunotherapy for locally advanced stomach cancer. Researchers will compare sorbitol against a placebo in 80 patients who will receive the treatment for 3 mo…

This is an early-stage study testing a new type of cell therapy for people with moderate to severe lupus that hasn't responded to standard treatments. The therapy, called CT1192, involves giving patients specially modified immune cells (CAR-T cells) designed to target and remove …

This is an early-stage study testing a new CAR-T cell therapy called IASO208 for adults with aggressive B-cell blood cancers that have come back or not responded to standard treatments. The main goal is to find a safe dose and see how the body handles the treatment, while also ch…

This early study is testing the safety of a new drug called A-319 for people with active rheumatoid arthritis (RA) who haven't gotten enough relief from at least two other standard treatments. The drug works by guiding the body's own immune T-cells to find and destroy harmful B-c…

This study is testing a new combination of three drugs for women with a specific, hard-to-treat form of cervical cancer that has spread, come back, or hasn't responded to prior treatment. The goal is to see if this combination can shrink tumors and control the disease. It is for …

This study is testing a comprehensive treatment approach for people with high-risk rectal cancer that hasn't spread to distant organs. All participants will receive one week of radiation followed by six cycles of combined chemotherapy and immunotherapy before surgery. The goal is…

This study is testing whether a specific phosphate supplement in granule form can safely and effectively raise low blood phosphorus levels in hospitalized ICU patients. It will involve 60 adults who have been diagnosed with this condition. Researchers will give the supplement by …

This early-stage study is testing a new type of cell therapy called universal CD19/CD20 CAR-T for people with moderate to severe lupus that hasn't improved with standard treatments. The main goals are to find a safe dose and see how the body reacts to the treatment. Researchers w…

This early-stage study is testing a new drug called A-319 for people with active or treatment-resistant lupus (SLE). The drug is designed to guide the body's own T cells to find and destroy harmful B cells that drive the disease. Researchers will enroll about 25 participants to p…

This early-phase study is testing the safety and initial effectiveness of a new cell therapy called OriV508 for adults with multiple myeloma or non-Hodgkin lymphoma that has returned or not responded to prior treatments. The therapy involves modifying a patient's own immune cells…

This is a very early study to test the safety and initial effects of a new experimental treatment called ZZSW-01 for adults with advanced B-cell blood cancers that have come back or not responded to standard therapies. The treatment involves giving patients modified immune cells …

This study is testing whether using artificial intelligence (AI) to help plan the placement of surgical screws is better than a surgeon planning alone for fixing broken hips. It will involve 334 adults with a hip fracture who need screw fixation. Researchers will compare if AI-as…

This study is testing whether a fecal microbiota transplant (FMT) can help critically ill ICU patients with severe, drug-resistant lung infections. Researchers will transfer gut bacteria from healthy donors to patients via a feeding tube, aiming to restore a healthy balance of ba…

This early-stage study is testing a new cell therapy called PRG-1801 for adults with immune thrombocytopenia (ITP) that has come back or hasn't responded to standard treatments. The main goal is to find a safe dose and see if the therapy helps increase platelet counts. Researcher…

This early-phase study is testing a new 'universal' CAR-T cell therapy called RD06-05 in adults with severe autoimmune blood diseases that haven't responded well to standard treatments. The main goal is to check the safety of two different doses and see how well the therapy works…

This early-phase study is testing a new type of cell therapy called CT1190B, a 'universal' CAR-T, for patients aged 12-75 whose B-cell acute lymphoblastic leukemia has come back or hasn't responded to other treatments. The main goals are to find a safe and effective dose and to s…

This early-stage study is testing a new drug called cizutamig in people with rheumatoid arthritis that hasn't responded to standard treatments. The research aims to see if the drug is safe and shows signs of helping control the disease. About 28 participants will receive the drug…

This is an early, exploratory study to test the safety and initial effects of a new cell therapy called CT1195E in people with severe, worsening systemic sclerosis (scleroderma). The therapy involves collecting and genetically modifying a patient's own immune cells (CAR-T cells) …

This study is for people with advanced liver disease (cirrhosis) who have lost significant muscle mass (sarcopenia) and need a standard procedure called TIPS to treat internal bleeding or fluid buildup. Researchers want to see if adding a specific nutritional supplement (branched…

This study is testing a new imaging method called FL-091 to see if it can better detect and determine the stage of certain cancers. It involves injecting a small amount of a radioactive tracer that seeks out a specific protein found on many cancer cells. Researchers will scan 100…

This study is testing three new types of PET scans to see if they can better detect and assess kidney cancer. Researchers will use these scans on people suspected of having kidney cancer and on healthy volunteers. The goal is to see if these new scans can provide clearer pictures…

This early study is testing a new type of PET scan (using a tracer called 68Ga-FL-031) to see if it can help doctors better find, identify, and determine the stage of certain cancers. It will involve about 10 adults with suspected or confirmed cancers like small cell lung cancer,…

This study aims to see if a simple blood test can predict which patients recovering from viral heart inflammation will develop a serious heart muscle disease called dilated cardiomyopathy. Researchers will follow 300 patients for up to 5 years, checking their blood for specific a…

This study is testing a new type of PET scan designed to find cancers in the stomach, pancreas, bile ducts, and esophagus. It uses a special tracer that attaches to a protein called CLDN18.2, which is often found on these cancer cells. The goal is to see if this scan can accurate…

This study aims to understand the link between a person's nutritional status and the progression of bronchiectasis, a chronic lung disease. Researchers will enroll 300 adults with bronchiectasis and measure various nutrition and body composition indicators, then follow them for t…

This study aims to understand how and why long-term, low-dose antibiotic treatment helps some people with bronchiectasis, a chronic lung disease. Researchers will follow 150 adult patients for two years, collecting sputum, stool, and blood samples to analyze their microbes and bo…

This study aims to use artificial intelligence (AI) to analyze standard CT scans from liver cancer patients. The AI will look at body composition, like muscle and organ health, to understand a patient's overall condition. The goal is to create a tool that helps doctors better pre…

This study aims to understand how a standard liver procedure (TIPS) might help improve severe muscle loss (sarcopenia) in people with advanced liver cirrhosis. Researchers will follow 132 patients after their TIPS surgery, measuring a specific protein (FGF21) in their blood and t…