Union Hospital, Tongji Medical College, Huazhong University Of Science And Technology

This study is testing a specific sequence of three different medications to treat severe immune thrombocytopenia (ITP), a condition where the immune system attacks blood platelets. Adults with very low platelet counts will first receive two drugs in the hospital for two weeks, th…

This early-stage study aims to test the safety and initial effects of an experimental drug called YKST02 in adults with IgA nephropathy, a common kidney disease. The trial will enroll 12 participants who still have protein in their urine despite standard treatments. Researchers w…

This early-stage study is testing the safety and initial effectiveness of a new type of cell therapy called RD06-05 for adults with moderate-to-severe ulcerative colitis or Crohn's disease. The therapy involves modifying a patient's own immune cells to target and reduce inflammat…

This study is testing whether adding two immunotherapy drugs (pembrolizumab and MRG-003) before and after standard chemoradiation can better control advanced nasopharyngeal cancer. It will involve about 35 adults with a specific type of this cancer linked to the Epstein-Barr viru…

This study is testing whether adding a new immunotherapy drug called cadonilimab to standard chemotherapy and radiation works better than standard treatment alone for locally advanced cervical cancer. It will involve 378 women with stage IIB-IVA cervical cancer who haven't had pr…

This study is testing if adding a special, short-course radiation schedule to a new immunotherapy drug and standard chemotherapy can better control advanced lung cancer. It will involve about 104 adults with a specific type of lung cancer that has spread and lacks certain genetic…

This is an early-stage study to test the safety and initial effectiveness of a new cell therapy called QI-019A in adults with multiple myeloma that has come back or stopped responding to standard treatments. The therapy involves modifying a patient's own immune cells to target th…

This large Phase 3 trial is testing whether a gentler treatment approach works as well as standard care for advanced nasopharyngeal cancer. Researchers want to see if they can replace harsh concurrent chemotherapy with immunotherapy (serplulimab) after initial chemotherapy, aimin…

This early-stage study is testing the safety and initial effectiveness of a new cell therapy called YTS109 for adults with severe autoimmune hemolytic anemia (AIHA) who have not improved after at least three other treatments. The study will enroll about 13 participants to find a …

This study is testing a new pre-surgery treatment for patients with a type of esophageal cancer that can be removed by surgery. It combines a short course of radiation with an immunotherapy drug (serplulimab) and two chemotherapy drugs. The goal is to shrink the tumor as much as …

This study is testing an experimental drug called IBI363 in people with advanced small cell lung cancer that has continued to grow despite previous treatments, including immunotherapy. The trial will enroll 35 patients to see how well the drug shrinks tumors and how safe it is. P…

This early-phase study is testing a new type of cell therapy called QT-019C in adults with a hard-to-treat form of immune thrombocytopenia (ITP), a disorder where the immune system attacks platelets. The main goal is to check if the treatment is safe and to look for early signs t…

This study is testing whether penfluridol, a medication long used for mental health, can help control aggressive small cell cancers of the lung or cervix that have returned or stopped responding to standard treatments. It will enroll 33 adults who have already tried at least two …

This study is testing a new two-drug combination for women with advanced cervical, vulvar, or vaginal cancer that has returned or spread. It aims to see if the treatment is safe and effective for up to 30 participants who have already tried standard therapies. The approach combin…

This study is testing whether a fecal microbiota transplant (FMT) can help treat delirium in critically ill patients in the intensive care unit (ICU). Researchers will give 60 ICU patients with delirium either the FMT treatment or standard care to see if restoring healthy gut bac…

This study aims to find out which of two advanced imaging methods is better at detecting and staging liver cancer. Researchers will compare a new type of PET scan (called XH06) against a standard enhanced MRI scan in 150 adults suspected or diagnosed with liver cancer. The goal i…

This study is testing a new type of PET scan designed to improve the detection and staging of colorectal, gastric, and pancreatic cancers. It uses a special imaging agent that targets a protein called GPA33, which is often found on these cancer cells. The goal is to see if this n…

This study is testing a new type of medical scan to see if it can better detect and locate liver cancer tumors. It will involve 6 people who have or are strongly suspected to have liver cancer. The main goal is to see how a special imaging agent moves through the body, if it's sa…

This study is testing if a common steroid nasal spray can prevent a frequent and painful side effect of radiation therapy for a type of head and neck cancer. The side effect, fluid buildup in the middle ear, often leads to hearing loss and a feeling of fullness, sometimes requiri…

This study is testing a new injection called ALT001 to see if it can safely reduce pain and improve movement in people with knee osteoarthritis. 30 participants will receive either a placebo or one of two doses of ALT001, injected into the knee every two weeks for six treatments.…

This study aims to understand how anxiety and depression might be linked to more frequent flare-ups in people with bronchiectasis, a chronic lung disease. Researchers will enroll 300 adults with the condition to track their mental health and disease progression over five years. T…

This research aims to understand how nasopharyngeal cancer changes and resists immunotherapy over time. Researchers will analyze tumor tissue samples from 600 patients who have already received standard treatment. The goal is to identify specific biological markers that predict t…

This study looks back at data from 1,000 past lung cancer patients to see if artificial intelligence (AI) can better predict outcomes. The AI analyzes patients' CT scans, tissue samples, and genetic test results to learn which patients are most likely to stay cancer-free after su…

This study is testing a new, non-invasive monitoring method for critically ill patients in the ICU. Researchers want to see if a special chest belt using safe electrical signals can accurately measure heart and lung function, matching the accuracy of the current standard method w…