Scientists probe immune cell shifts in ICU patients to unlock sepsis secrets

NCT ID NCT07680816

Not yet recruiting Knowledge-focused Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study examines how a type of immune cell called gamma delta T cells adapt and function in critically ill patients, both with and without sepsis. Researchers will compare these cells in healthy people, non-septic ICU patients, and septic ICU patients. The goal is to understand why the immune system sometimes fails in sepsis, which could lead to better treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new treatments for immune problems in sepsis and critical illness.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to direct therapies, and findings may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Critical Illness Dysbiosis inborn mitochondrial metabolism disorder infectious disease with sepsis mitochondrial disease multiple organ dysfunction syndrome Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS DYSBIOSIS IMMUNOSUPPRESSION MITOCHONDRIAL DISEASES MODS SEPSIS ΓΔ T CELLS

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