Can a simple protein tame Sepsis's fiery inflammation?
NCT ID NCT03950778
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This trial asks whether giving extra albumin—a key protein in the blood—can lower inflammation and oxidative stress in people with sepsis, a severe infection that can cause organ failure. Adults in intensive care with sepsis and low albumin levels are randomly assigned to receive either albumin infusions for three days or standard care. Researchers will track changes in inflammatory markers like C-reactive protein and procalcitonin, as well as antioxidant capacity, to see if albumin supplementation offers a protective effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Human albumin solution (20%) given intravenously for three days
- What this could lead to
- If albumin helps, it could point toward a simple supportive therapy to ease inflammation and oxidative stress in sepsis patients in intensive care.
- What could go wrong
- This is a very early, small trial, so results may not be conclusive. Albumin is generally safe, but any IV therapy carries risks like allergic reactions or fluid overload.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universitty of Pecs Department of Anaesthesiology and Intensive Therapy
Pécs, Ifjúság Str.13., 7624, Hungary
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University of Pécs Department of Anaesthesiology and Intensive Therapy
Pécs, Ifjúság Str 13., 7524, Hungary
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