Fertility shield: goserelin injection may preserve ovarian function after stem cell transplant
NCT ID NCT07552493
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a single injection of goserelin, given just before a stem cell transplant, can help preserve ovarian function in women with blood cancers. The trial will enroll 64 women aged 14 to 50 and measure if their menstrual cycles return naturally within six months after the transplant. The goal is to reduce the risk of early menopause and infertility caused by the high-dose chemotherapy used in the transplant.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- goserelin
- What this could lead to
- If it works, this could offer a way to protect fertility and ovarian function in women undergoing stem cell transplants for blood cancers.
- What could go wrong
- This is a small, early-stage trial with only 64 participants. The drug may not improve menstrual recovery, and there could be side effects from the hormone suppression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, 450000, China
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China
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The First People's Hospital of Yunnan Province
Kunming, Yunnan, 650000, China
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430000, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430000, China
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