Triple-Drug combo aims to stop AML relapse after remission

NCT ID NCT07521124

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a combination of three drugs (chidamide, venetoclax, and azacitidine) can help prevent acute myeloid leukemia (AML) from coming back in patients who have already achieved remission. About 104 adults aged 18 to 80 will receive up to 12 cycles of treatment. The goal is to see if this maintenance therapy improves relapse-free survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
chidamide, venetoclax, and azacitidine
What this could lead to
If successful, this maintenance regimen could help keep AML in remission longer and reduce the chance of relapse.
What could go wrong
This is an early-phase study with no phase specified, so results are uncertain. The combination may cause side effects and may not improve survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technolog

    Wuhan, China

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