Stem cell shot could fix Worn-Out knees

NCT ID NCT07547735

Recruiting now Disease control Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests whether a single injection of stem cells from umbilical cords can help people with knee osteoarthritis. 100 adults aged 40-70 will receive either a low or high dose of stem cells or a placebo. The study measures changes in pain, stiffness, and function over time, aiming to find a treatment that goes beyond just symptom relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: umbilical cord mesenchymal stem cells (UC-MSCs)
What this could lead to: If it works, this could point toward a new treatment that repairs cartilage and reduces pain in knee osteoarthritis, potentially delaying or avoiding joint replacement.
What could go wrong: This is an early Phase 2 trial with only 100 people, so results may not apply to everyone. The treatment is a single injection, and its long-term safety and effectiveness are still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Guangzhou First People's Hospital
RECRUITING

Wuhan, China
Wuhan Fourth Hospital
RECRUITING

Wuhan, China
Wuhan Third Hospital
RECRUITING

Wuhan, China

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