New combo therapy may let some rectal cancer patients avoid surgery

NCT ID NCT07474103

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment plan for people with high-risk rectal cancer that hasn't spread. Patients get a short course of radiation, then a mix of chemotherapy and immunotherapy before considering surgery. If the cancer disappears completely, patients may choose a 'watch and wait' approach instead of immediate surgery. The goal is to see if this approach improves outcomes and possibly avoids the need for surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hongli Liu

    RECRUITING

    Wuhan, China

    Contact Phone: •••-•••-••••