New injection could train your body to fight cancer from within

NCT ID NCT07240974

Recruiting now Disease control Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new drug called ZZSW-01 in 6 people with B-cell blood cancers that have come back or not responded to other treatments. The drug is a special particle that carries instructions for the body to make its own cancer-fighting cells. The main goal is to check safety and find the right dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ZZSW-01 injection (a type of CAR mRNA therapy delivered via extracellular vesicles to create CAR-T cells inside the body)
What this could lead to: If successful, this could lead to a new, simpler way to treat certain blood cancers without needing to extract and modify a patient's own cells.
What could go wrong: This is a very early, tiny study with only 6 participants, so results may not apply broadly. There are risks of serious side effects like cytokine release syndrome and nerve toxicity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma precursor B-cell acute lymphoblastic leukemia Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSED/REFRACTORY B-CELL MALIGNANCIES

Contacts and locations

Locations

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, 430022, China

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