New study aims to crack the code of treatment resistance in lymphoma

NCT ID NCT07614035

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 70 adults with relapsed or refractory B-cell non-Hodgkin lymphoma who are receiving bispecific antibody therapy. Researchers want to understand why some patients don't respond or develop serious side effects. They will look at tumor samples, gut bacteria, and PET scans to find clues that could predict treatment success or failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bispecific antibodies (glofitamab, epcoritamab, mosunetuzumab)

What this could lead to

If successful, this could help doctors choose the best treatment for each patient and identify who might benefit most from bispecific antibody therapy.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not lead to immediate changes in care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Policlinico di Sant'Orsola

    Bologna, Emilia-Romagna, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••