Could a simple scan reveal which cancers are hiding a dangerous protein?

NCT ID NCT07301814

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new PET imaging probe that targets a protein called CLDN18.2, found in some stomach, pancreatic, bile duct, and esophageal cancers. Researchers will scan 56 people (patients and healthy volunteers) to see if the scan can accurately detect tumors and guide treatment choices. The goal is to improve diagnosis and help doctors decide who should receive CLDN18.2-targeted therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CLDN18.2-specific PET imaging probe (a radioactive tracer)

What this could lead to

If successful, this imaging method could help doctors better identify which patients might benefit from CLDN18.2-targeted therapies, improving personalized cancer treatment.

What could go wrong

This is an early-stage imaging study with only 56 participants, so results may not apply broadly. The tracer's safety and accuracy are still being evaluated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma esophageal cancer Esophageal Neoplasms gastric cancer gastric neoplasm malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wuhan Union Hospital, China

    RECRUITING

    Wuhan, Hubei, 430030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••