PANCREATIC CANCER

This study tests whether combining two existing cancer drugs (pembrolizumab and olaparib) can help control advanced pancreatic cancer that has spread and has specific genetic features. The trial will enroll 20 patients who have already tried one prior treatment. Researchers will …

This early-stage study is testing a new type of personalized immune cell therapy for people with advanced solid tumors, like pancreatic cancer, that have specific KRAS gene mutations. Doctors will collect a patient's own T-cells, modify them in a lab to better recognize and attac…

This is an early-stage study testing the safety of a new cell therapy called IX001 TCR-T for people with advanced pancreatic cancer that has a specific KRAS G12V mutation. Researchers will modify a patient's own immune T-cells in a lab to better recognize and attack their cancer,…

This early-stage study is testing a new implant called PTM-101, which is placed near the pancreas to deliver chemotherapy directly to the tumor. The goal is to see if this approach, combined with standard pre-surgery chemo, is safe and can shrink tumors in people with borderline …

This study is testing whether adding one or two new drugs (ivonescimab and AK117) to standard chemotherapy works better than chemotherapy alone for people with advanced pancreatic cancer that has spread. About 1,000 participants will be randomly assigned to receive either the new…

This study is testing whether adding a new drug called setidegrasib to standard chemotherapy helps people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D mutation) live longer. About 614 adults whose cancer has spread and cannot be cured by surgery w…

This study is testing a combination of three treatments—an immunotherapy drug (atezolizumab), a new immune-stimulating drug (BDB001), and targeted radiation—to see if they can better control advanced solid tumors. It is enrolling 247 adults with specific advanced cancers, includi…

This study is testing whether tiny radioactive seeds can be safely placed directly into pancreatic tumors to deliver radiation. It's for 15 patients with advanced pancreatic cancer who have already tried chemotherapy or cannot have surgery. The main goals are to see if doctors ca…

This early-stage study is testing a new drug called BL-M17D1 in adults with advanced gastrointestinal cancers and other solid tumors that have a specific marker called HER2. The main goal is to find the safest dose and see how the body processes the drug. Researchers will also ch…

This early-stage study is testing the safety and effects of an experimental cancer drug called PF-08046876 in adults with advanced solid tumors. The drug is an antibody drug conjugate designed to target and kill cancer cells. Researchers will give the drug through an IV to about …

This study is testing whether a new drug called daraxonrasib, given alone or with standard chemotherapy, works better than chemotherapy alone for people with advanced pancreatic cancer that has spread. About 900 participants will be randomly assigned to receive one of three treat…

This study is testing a combination of two investigational drugs, AK130 and AK112, for people with advanced pancreatic cancer that has worsened after up to two prior treatments. The main goals are to see if the drug combination is safe and if it can shrink tumors. The trial will …

This study is testing a new, personalized vaccine designed to teach the immune system to attack leftover cancer cells after surgery. It is for people with colorectal or pancreatic cancer who have a specific genetic change (KRAS mutation) and a high risk of the cancer returning. T…

This early-stage study is testing a new cell therapy for people with advanced ovarian or pancreatic cancer that has stopped responding to standard treatments. Doctors are giving patients specially modified immune cells, called CAR-NK cells, directly into the abdomen to try to att…

This study is testing if a special surgical glue can prevent dangerous fluid leaks after major pancreas cancer surgery. About 194 patients having surgery for pancreatic or related cancers will be randomly assigned to receive the standard surgical connection or the same connection…

This study is testing a smartphone app that uses artificial intelligence to monitor patients' nutrition and health after surgery for pancreatic cancer. It will track things like weight, appetite, and strength to help spot nutritional problems early. The goal is to see if this AI …

This program provides access to an investigational drug called ulixertinib for patients with advanced cancers that have specific genetic changes (MAPK pathway mutations). It is for people who have run out of other treatment options. The drug aims to control the cancer's growth, e…

This study is testing an experimental drug called M9140 in people with advanced gastric, lung, or pancreatic cancer that has stopped responding to standard treatments. The trial aims to see if M9140 can shrink tumors and is safe for patients. It will enroll about 250 adults whose…

This study is testing which of two radiation therapy methods works better to shrink pancreatic tumors before surgery. About 102 patients with pancreatic cancer that might be removable by surgery will be randomly assigned to receive either a newer, shorter radiation treatment or a…

This study is testing a personalized approach to treat pancreatic cancer before surgery. Doctors will analyze a small tumor sample to determine its genetic subtype. Based on this result, patients will receive one of two standard chemotherapy regimens that is predicted to work bes…

This early-stage study is testing a new drug called MRG007 in people with advanced solid tumors that have spread and cannot be surgically removed. The main goals are to find a safe dose and see if the drug helps shrink tumors in patients with colorectal, gastric, pancreatic, and …

This study is testing a precise, high-dose radiation treatment for liver tumors that cannot be surgically removed. It is designed for patients whose tumors are too large or located too close to major blood vessels or sensitive organs for standard heat-based treatments. The goal i…

This study is testing whether adding a new immunotherapy drug (QL1706) to standard chemotherapy works better for people with advanced pancreatic cancer that cannot be removed by surgery. It will involve 58 adults who have not yet received any treatment for their advanced cancer. …

This is a first-in-human study to test the safety and early effectiveness of a new cell therapy called CAR-NK cells in patients with advanced pancreatic cancer. The study will enroll a small group of patients whose cancer has progressed despite standard treatments. The main goal …

This is the first human study of an experimental oral drug called AOH1996 for patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest dose and understand how the body processes the drug. Researchers will enrol…

This study is testing if using a patient's genetic information to personalize their chemotherapy dose is better than the standard approach. It will enroll 178 adults with pancreatic or colorectal cancer who are starting treatment. The main goal is to see if the personalized dosin…

This study tests whether combining proton radiation therapy with oral chemotherapy can help more people with pancreatic cancer become eligible for surgery. It focuses on patients whose tumors are currently considered inoperable or borderline operable. The goal is to shrink tumors…

This study is testing whether removing the entire pancreas is better than removing just part of it for patients with cancer in the head of the pancreas who are at high risk of a dangerous leak after surgery. Researchers will randomly assign 170 patients to receive either the stan…

This is the first study in people testing a new cancer drug called AGX101. It aims to find a safe and effective dose for patients with advanced solid tumors that have spread or cannot be removed by surgery, and who have no other standard treatment options left. The drug is given …

This study is testing a new combination of drugs for people newly diagnosed with metastatic pancreatic cancer. The main goal is to check if the treatment is safe and to see if it can help control the cancer. Researchers will measure how long patients live without their cancer get…

This early-stage study is testing a new drug called RMC-5127 in adults with advanced cancers that have a specific genetic change called KRAS G12V. The main goals are to find a safe dose and see how the body processes the drug, both when given alone and when combined with other ca…

This early-stage study is testing a new oral drug called VMD-928, both by itself and combined with an existing immunotherapy (pembrolizumab). It is for adults with advanced solid tumors or lymphoma that have progressed despite available treatments. The main goals are to find safe…

This study is testing whether a personalized cancer vaccine, given along with standard chemotherapy and immunotherapy, can help prevent pancreatic cancer from coming back after surgery. It will involve 28 patients whose tumors have been surgically removed. The main goal is to see…

This early-stage trial is testing a new treatment for people with metastatic pancreatic or breast cancer. The goal is to see if a combination of high-dose chemotherapy drugs, vitamins, and the patient's own stem cells is safe and can overcome the cancer's resistance to treatment.…

This is the first human study of an experimental drug called PT0511 for people with advanced solid tumors that have specific KRAS genetic changes. The main goals are to find safe doses and see how the body processes the drug, both alone and combined with another cancer medication…

This study is testing the safety of a new treatment for advanced pancreatic cancer. It combines tiny radioactive implants placed directly into the tumor with standard chemotherapy. The goal is to see if this approach can help control the cancer, reduce pain, and potentially make …

This study is testing new drug combinations for people with advanced pancreatic cancer that cannot be removed by surgery. Researchers will give 160 participants either a single new drug or combinations with other treatments to see how safe they are and if they can shrink tumors. …

This study is testing if adding a new drug called QLS31905 to standard chemotherapy works better than chemotherapy alone for adults with advanced pancreatic cancer that has a specific marker (CLDN18.2). It will involve about 602 people who have not yet received treatment for thei…

This study is testing a new type of radiation therapy called lattice radiation (LRT) for people with large cancer tumors that have spread to soft tissues. It compares LRT to standard radiation to see which is better at shrinking tumors and attracting immune cells to fight the can…

This study is testing a new drug called BI 765049, given alone and with another drug called ezabenlimab, for Asian adults with advanced cancers that have stopped responding to standard treatments. The main goals are to find safe doses and see if the treatment can shrink tumors by…

This early-stage trial is testing whether adding a new experimental drug called zunsemetinib to a standard chemotherapy regimen (mFOLFIRINOX) is safe and tolerable for people with newly diagnosed metastatic pancreatic cancer. The main goal is to find the right dose of the new dru…

This study is testing a new treatment for people with advanced pancreatic cancer that cannot be removed by surgery. Doctors take a patient's own immune cells, arm them in the lab to better recognize and attack cancer, and then infuse them back into the patient. The main goals are…

This early-stage study is testing a new drug called GI-108 in people with advanced or spreading solid tumors, including lung, head and neck, pancreatic, and kidney cancers. The main goals are to find a safe dose and see if the drug shows any signs of helping to shrink tumors. The…

This is the first study in people to test the safety and behavior of a new drug called azirkitug. It will be given alone and in combination with two other cancer drugs to adults with advanced solid tumors, including lung and head and neck cancers, who have already tried standard …

This study is testing two different combinations of cancer vaccines and immune-boosting drugs for people with pancreatic cancer that can be removed with surgery. The goal is to see which approach is safer and more effective at helping the immune system fight the cancer, both befo…

This study is testing an experimental drug called zanidatamab for people with advanced cancers that have a specific marker called HER2 and have stopped responding to prior treatments. It will enroll about 200 adults with various cancers including breast, lung, stomach, and ovaria…

This study is testing whether a low dose of radiation can help turn a patient's immune system against their pancreatic cancer, making it more responsive to a new immunotherapy drug. It combines this radiation with the drug and standard chemotherapy. The goal is to see if this thr…

This early-stage trial is testing whether a personalized cancer vaccine that targets specific mutations in tumors, combined with two immunotherapy drugs, can help control advanced colorectal or pancreatic cancer. The study is for patients whose cancer has spread and who have alre…

This program provides access to an experimental drug called AVM0703 for patients with various solid tumors and blood cancers. It is for people who may not have other treatment options. The drug aims to help the body's immune system fight cancer, and early reports show mostly mild…

This early-stage study is testing whether a targeted heat treatment, delivered via a special scope, is safe and tolerable when added to chemotherapy for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combined approach can help…

This early-stage trial is testing the safety and best dose of a new two-drug combination (ulixertinib and palbociclib) for people with advanced solid tumors that have stopped responding to standard treatments. It will enroll up to 45 adults, with a specific focus on metastatic pa…

This program provides access to an experimental treatment called DNG64-CAR-V for patients with advanced pancreatic cancer, sarcoma, or breast cancer who have no other effective options left. The treatment uses a specially engineered virus designed to target and kill cancer cells …

This is an early-stage study to test the safety of a new type of cell therapy called PTC13 CAR-T in adults with advanced solid tumors that have a specific marker (CEA). The main goal is to find the safest dose and see how well patients tolerate the treatment. The therapy involves…

This study is testing the safety of a new, non-invasive device called the HistoSonics Edison System. It uses focused ultrasound waves (histotripsy) to destroy pancreatic tumors in patients with advanced cancer who are not candidates for surgery. The goal is to see if this approac…

This is a first-in-human study to test the safety and find the right dose of a new investigational drug called LY4052031 for people with advanced or metastatic solid tumors. The drug is designed to target a specific protein found on many cancer cells, delivering its medicine dire…

This study is testing a new drug called GAIA-102 for people with advanced stomach or pancreatic cancer that has spread to the lining of the abdomen, causing fluid buildup. The drug is injected directly into the abdomen, either alone or combined with an existing immunotherapy drug…

This early-stage study is testing a new radioactive drug injection (177Lu-CTR-FAPI) for people with advanced cancers that have spread and no longer respond to standard treatments, focusing on pancreatic cancer. The main goals are to check if the treatment is safe, measure how muc…

This study is testing a new way to treat advanced pancreatic cancer by placing tiny radioactive seeds directly into the tumor. The seeds release a short-range radiation designed to kill cancer cells while sparing nearby healthy tissue. The main goals are to see if doctors can saf…

This trial is testing a new type of gene therapy for people with advanced pancreatic, colon, and other cancers that have a specific genetic change called KRAS G12V. Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer c…

This early-stage trial is testing a new treatment for advanced pancreatic cancer. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to recognize and attack cancer cells with a specific KRAS G12V mutation, and then infuse them back into the pati…

This early-stage study is testing whether specially engineered immune cells can help control advanced pancreatic cancer. Doctors take immune cells from a patient's own tumor, modify them in the lab to potentially fight cancer better, then infuse them back into the patient. The tr…

This study is testing whether adding a new drug called BOLD-100 to standard FOLFOX chemotherapy can better control advanced cancers of the colon, pancreas, stomach, and bile ducts. Researchers will first find the safest dose of BOLD-100 and then see if the combination helps slow …

This study is testing a personalized treatment approach for pancreatic cancer that can be surgically removed. Doctors will adjust a patient's chemotherapy based on how well the initial treatment is working, as measured by scans and blood tests. The goal is to see if this adaptive…

This study is testing a new combination of drugs (HRS-4642, gemcitabine, albumin-bound paclitaxel, and adebrelimab) for people with pancreatic cancer that doctors believe can be removed with surgery. The goal is to see if giving these drugs both before surgery (to shrink the tumo…

This first-in-human study is testing an experimental cancer treatment called IDOV-Immune, which uses a modified virus designed to infect and destroy cancer cells while boosting the immune system. The trial aims to find the safest dose and check for early signs that the treatment …

This is the first human study of an experimental cancer drug called LY4101174. Researchers want to find a safe dose and see if it can help control advanced cancers that have spread or returned after other treatments. The study will enroll about 490 people with various solid tumor…

This is the first study in people to test a new cancer drug called KIVU-107. The main goal is to find a safe dose and see how well the body handles it. It is for adults with advanced solid tumors that have spread or cannot be removed by surgery and have stopped responding to avai…

This is the first study in people testing a new experimental cancer drug called PHN-012. It aims to find a safe dose and see if it can shrink tumors in patients with advanced colon, lung, or pancreatic cancer who have no other standard treatments left. The study will enroll about…

This early-stage trial is testing a new oral drug called RSC-1255 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how well the drug is tolerated, both alone and combined with another medicati…

This study aims to see how well the drug T-DXd works in real-world settings for patients with advanced HER2-positive cancers who have already tried other treatments and have no good options left. It will follow about 100 patients with various solid tumors (excluding breast, lung,…

This study is testing a new drug called FMC-376 for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find a safe and effective dose and to see if the drug can shrink or control tumors. It is for patients whose cancer ha…

This study is testing whether a new oral drug, daraxonrasib, can help keep pancreatic cancer from coming back after surgery and chemotherapy. It will compare the drug to standard observation (no drug) in 500 patients who have had their tumor surgically removed and completed chemo…

This study is testing a specialized, high-dose radiation treatment for pancreatic cancer that adapts to a patient's daily anatomy. The main goal is to see if this precise approach can reduce severe stomach and intestinal side effects compared to standard methods. It will also tra…

This study is testing a new type of personalized cancer treatment called CAR-T cell therapy. Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer cells that have a specific marker called CD70, and then infuse them back …

This study is testing whether closely monitoring and managing blood sugar levels might help people with pancreatic cancer respond better to chemotherapy. About 50 participants will use continuous glucose monitors while receiving standard chemotherapy. Half will aim for tight bloo…

This study is testing a new blood test designed to detect five different cancers (breast, colon, pancreatic, ovarian, and lung) at an early stage. Researchers will analyze tiny particles in the blood using a special light-based technique and artificial intelligence. The goal is t…

This study is testing a new imaging system designed to help surgeons better see cancer cells during operations for gastrointestinal cancers. Patients scheduled for surgery for colorectal, pancreatic, or esophageal cancer receive an intravenous imaging agent before their procedure…

This study is testing whether regular screening with MRI or a special ultrasound can help find early pancreatic cancer or pre-cancerous changes in people who have a high inherited risk due to specific gene mutations (BRCA1, BRCA2, ATM, or PALB2). Researchers will follow 200 parti…

This study is testing a new diagnostic platform called IT-TCP that analyzes tumor samples from patients with high-risk cancers. Researchers will collect samples from 300 patients with various cancers including leukemia, pancreatic cancer, and melanoma to see if this detailed anal…

This study is testing whether a simple rectal mucus sample can detect lung, pancreatic, bladder, and colorectal cancers by looking for DNA changes. Researchers will collect samples from 450 people using a special swab device to see if cancer-related genetic markers appear in the …

This study is testing a small, portable device called the P4 to improve the accuracy of MRI scans used to monitor pancreatic cancer. The goal is to reduce errors between different MRI machines and over time, so doctors can better see if a patient's treatment is working by measuri…

This study is testing new radioactive tracer chemicals for PET/CT scans to see if they can better detect and monitor cancers of the digestive system, including stomach, colon, liver, and pancreatic cancer. About 400 adults with confirmed or suspected digestive cancer will receive…

This study aims to create a simple blood test to find pancreatic cancer at its earliest, most treatable stages and to track how well treatment is working. Researchers are enrolling 700 people, including those with pancreatic cancer, pancreatitis, pancreatic cysts, and healthy vol…

This study aims to develop better tools to predict which pancreatic cysts might turn into cancer. Researchers will collect medical scans, blood samples, and health information from over 1,100 people with pancreatic cysts or tumors. By analyzing this data, they hope to create non-…

This study is testing whether adding an MRI scan to the standard CT scan helps doctors make better decisions about who should have pancreatic cancer surgery. Researchers want to see if the MRI finds small liver metastases that the CT misses, which would mean surgery isn't the rig…

This study is testing a new type of imaging scan called PYLARIFY PET-CT. The goal is to see if it can more accurately detect when cancer has spread (metastasized) in patients with pancreatic, liver, or breast cancer. Researchers will compare the new scan's results to current stan…

This study is testing an artificial intelligence (AI) tool called PANDA Pro to see if it can help doctors detect pancreatic cancer earlier on standard CT scans. It will involve up to 100,000 patient scans from a major hospital to check if the AI can find cancers that might otherw…

This study is testing a new method to detect breast, lung, and pancreatic cancers through a blood test. Researchers will measure specific enzyme levels in blood samples from 220 participants, including cancer patients and healthy volunteers. The goal is to see if this test can di…

This study aims to develop a better way to diagnose type 3c diabetes, which is caused by pancreatic cancer or chronic pancreatitis. Researchers will give participants a standardized meal drink and measure their body's hormone responses to see how they differ from regular type 2 d…

This study is testing a new artificial intelligence (AI) system designed to help doctors diagnose and manage pancreatic diseases from CT scans. It will compare the AI's recommendations for surgery or monitoring against the decisions of experienced doctors in 2,000 patients. The m…

This study is testing a new type of ultrasound imaging that combines multiple techniques to create more detailed pictures of tissue. Researchers want to see if this advanced imaging can better examine pancreatic cancer and thyroid nodules compared to standard ultrasound. The stud…

This study aims to confirm if a new blood test can find pancreatic cancer at its earliest, most treatable stages. Researchers will test the method in 2,000 people, including those with and without pancreatic cancer. The test looks for tiny genetic signals in the blood that may in…

This study is developing a simple breath test to help detect pancreatic cancer earlier. It will involve about 1,000 people, including those with pancreatic cancer, other pancreatic conditions, and general stomach issues. Researchers will analyze tiny molecules in breath to see if…

This study is testing a new, non-invasive breath test designed to help detect pancreatic cancer earlier. It will involve over 6,000 adults who have been referred by their doctor for possible pancreatic cancer due to vague symptoms. The goal is to see if the test can accurately id…

This study is testing a new blood test designed to detect many types of cancer early, before symptoms appear. It will involve 7,000 people, both with and without cancer, to see if the test can accurately spot cancer signals and identify where in the body the cancer started. The t…

This study is testing a new type of PET scan designed to find cancers in the stomach, pancreas, bile ducts, and esophagus. It uses a special tracer that attaches to a protein called CLDN18.2, which is often found on these cancer cells. The goal is to see if this scan can accurate…

This early-stage study is testing a new vaccine designed to prevent pancreatic cancer in people at high genetic risk. The vaccine aims to train the immune system to attack cells with a specific cancer-linked mutation. Researchers will enroll 37 participants to check if the vaccin…

This study is testing whether a remote exercise and nutrition program is practical and helpful for people preparing for pancreatic cancer surgery. Researchers want to see if patients can complete the program and if it improves their strength and recovery. The study will compare o…

This small early-stage study is testing whether oral ketamine can safely help reduce anxiety in people with pancreatic cancer. Twenty participants will receive either ketamine or a placebo pill in a crossover design to see if the treatment is practical and tolerable. The main goa…

This study is testing whether a remote support program can help pancreatic cancer patients maintain their weight and nutrition after surgery. The program provides extra access to a dietitian and uses a mobile app for food tracking. Researchers want to see if patients find it help…

This study is testing whether a program of supervised strength training exercises, with or without protein shakes, is practical and helpful for people with pancreatic cancer who are starting chemotherapy. The main goal is to see if this approach can help patients maintain or buil…

This study compares how well the cancer drug T-DXd works compared to standard treatments for patients with advanced HER2-positive solid tumors. Researchers will analyze existing medical records from about 105 patients who received either T-DXd in previous trials or standard care …

This study aims to understand how pancreatic cancer changes at a molecular level during standard chemotherapy treatment. Researchers will collect small tumor samples from 80 patients with non-metastatic pancreatic cancer before and after they receive chemotherapy. By analyzing th…

This study aims to see if special CT scans taken before and during cancer treatment can help doctors predict how well chemotherapy will work for patients with pancreatic or liver cancers. Researchers are enrolling 259 people with these cancers who are scheduled to receive standar…

This study aims to discover new biological markers that could help detect gastrointestinal cancers earlier. Researchers are collecting tissue, blood, urine, and stool samples from 5,000 people undergoing colonoscopy, endoscopy, or surgery. The goal is to identify substances that …

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study aims to understand how obesity might contribute to the development and progression of pancreatic cancer, particularly in African American adults. Researchers will observe and compare biological samples from about 125 adults who are African American or Non-Hispanic Whit…

This study aims to understand the link between the body's bacteria (microbiome) and pancreatic cancer. Researchers will collect samples from 300 adults who are already scheduled for a pancreas exam. The goal is to find bacterial patterns that could help doctors diagnose cancer ea…

This study aims to understand what causes pancreatic cancer by collecting health information and blood samples from 10,000 people. It includes people with pancreatic cancer, those at high risk, and healthy individuals for comparison. The data and samples will be stored to help fu…

This study aims to find out if a diabetes medication called exenatide increases the risk of pancreatic cancer compared to other diabetes drugs. Researchers will analyze the health records of 24,000 type 2 diabetes patients across Europe from 2006 to 2023. The study is observation…

This study aims to discover new genes that cause cancer to run in families, especially those affecting children. Researchers will collect health information, blood, and sometimes leftover tumor samples from families where multiple members have had cancer. The goal is to build a l…

This study is creating a large collection of medical information and biological samples from people with various pancreatic conditions. Researchers will collect blood, saliva, leftover tissue, and survey data from up to 20,000 participants. The goal is to build a resource that he…

This study aims to understand how a specific chemotherapy drug works for pancreatic cancer patients in everyday medical practice, not a controlled trial. It will observe 3000 patients in China who are already receiving this treatment to collect information on side effects and how…

This study aims to see if a special type of MRI scan, which measures how stiff a pancreatic tumor is, can help doctors predict how patients will respond to chemotherapy and how long they might live. Researchers will scan 200 adults with pancreatic cancer and compare the stiffness…

This study aims to understand how pancreatic cancer communicates and spreads by examining tiny particles called exosomes in the blood and tissue. Researchers will compare samples from 181 patients with pancreatic cancer to those with non-cancerous pancreatic conditions to establi…

This study aims to learn if finding cancer cells or cancer DNA in a person's blood, urine, or bone marrow can help doctors better understand how cancer spreads. Researchers will collect samples from 100 people with cancer and 200 people at high risk for lung cancer to see if thes…

This study is testing whether a short educational video can be a good alternative to standard genetic counseling for patients with certain cancers. Researchers want to see if the video helps people understand their risk for hereditary cancers and makes genetic testing information…

This study aims to better understand cancer cachexia—a condition where patients lose muscle and weight, which can worsen outcomes even for those undergoing potentially curative surgery. Researchers will track 200 UK patients with certain digestive cancers, along with a small comp…

This study aims to collect blood and tissue samples from people with various cancers to help develop better blood tests. Researchers want to see if these tests can detect tiny amounts of leftover cancer cells after treatment, which might help predict if the cancer could return. P…

This study is building a large, long-term database of health information and biological samples from people with cancer, people at risk for cancer, and healthy volunteers. The goal is to collect this data to help researchers better understand what causes cancer and how to prevent…

This study is collecting real-world information about how advanced pancreatic cancer is treated in Austria. It will follow 1,500 adult patients to see which treatments are used, how well they work, and what side effects patients experience. The goal is to gather knowledge from ev…

This study aims to understand advanced pancreatic cancer better by analyzing the genetic makeup of patients' tumors. Researchers will collect tumor samples and blood from about 190 patients starting chemotherapy to look for patterns in their genes. The goal is to see if these gen…

This study is testing a new AI tool designed to spot a serious condition called cachexia (severe weight and muscle loss) early in people with pancreatic cancer. It also aims to see if personalized diet and exercise plans are practical and acceptable for patients to help manage th…

This study is testing a new laboratory method to see if it can predict which cancer treatments will work best for a patient. Researchers will take a sample of a patient's tumor cells from a fluid or tissue biopsy and test how the cells react to different drugs in the lab. The goa…

This study is testing a new type of PET scan to see if it can better detect pancreatic cancer and its potential spread. Researchers will compare this new scan, which uses a special radioactive tracer, to the standard CT scan. The goal is to learn if the new method provides more u…

This study aims to learn which of three standard procedures works best for treating stomach blockages caused by pancreatic cancer. Researchers will observe 250 patients who receive either surgery, an internal metal stent, or a newer endoscopic bypass procedure. They will compare …

This small pilot study is testing whether patients undergoing cancer treatment will consistently use a commercial fitness tracker to collect heart rate data. Researchers want to see if the devices are easy to use and if the collected data can help them learn more about cancer-rel…

This study is creating a large registry of people at high risk for pancreatic cancer to help researchers find better ways to detect the disease early. It will collect blood samples, pancreatic fluid, and medical images from 5,000 participants over ten years. The goal is to use th…

This study is testing a new way to collect blood for cancer detection. Researchers want to see if taking blood from a vein directly draining the cancer during a biopsy finds more tumor DNA than a standard blood draw from the arm. The goal is to improve the accuracy of blood tests…

This study aims to collect tumor tissue and blood cells from people with advanced solid tumors to prepare for future CAR T-cell therapy. Researchers will analyze the cancer tissue to understand how tumors hide from the immune system and collect participants' own immune cells thro…

This early study is testing the safety of a tiny, implantable device in patients with pancreatic cancer who are already scheduled for surgery. The device, placed and removed during the operation, releases tiny amounts of different chemotherapy drugs into the tumor tissue to see h…

This study aims to create better educational materials about genetic testing for cancer patients who speak different languages and come from diverse cultural backgrounds. Researchers will work with 445 patients who have breast, ovarian, prostate, pancreatic, or colorectal cancer …

This study aims to learn how radiation therapy changes the environment inside and around tumors in cervical and pancreatic cancer. Researchers will collect tissue samples, blood, and imaging data from 60 patients before, during, and after their standard radiation and chemotherapy…

This study aims to see if changes in what people buy—like pain relief or digestive aids—can serve as an early warning sign for certain cancers. Researchers will compare the shopping history of 1,450 recently diagnosed cancer patients with 1,450 people without cancer, using up to …

This study aims to learn more about pancreatic cysts, which are fluid-filled sacs in the pancreas often found by accident on scans. Researchers will follow 4,000 adults with these cysts over time to see which ones stay harmless and which might develop into cancer. The goal is to …