New drug GI-108 aims to boost immune attack on Hard-to-Treat cancers

NCT ID NCT07172802

First seen Sep 30, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tests a new drug called GI-108 in people with advanced or metastatic solid tumors (like lung, head and neck, pancreatic, or kidney cancer). The drug is designed to help the immune system fight cancer by targeting a protein called CD73 and delivering a modified immune signal (IL-2). The trial has two parts: first, finding the safest dose, then checking how well the drug shrinks tumors. About 76 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

    Contact Email: •••••@•••••

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yonsei University Health System, Severance Hospital

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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