Could a common anesthetic slow pancreatic cancer spread?
NCT ID NCT04048278
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether a lidocaine infusion given during pancreatic cancer surgery can affect circulating tumor cells (CTCs) — cancer cells that may travel through the blood. Researchers will compare lidocaine to a saline placebo in patients undergoing robotic pancreatectomy. The goal is to see if lidocaine changes the activity of these cells, potentially reducing the risk of cancer spread.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lidocaine Hydrochloride
What this could lead to
If lidocaine is found to affect cancer cell activity, it could point toward a new way to slow spread during surgery.
What could go wrong
This is an early-phase study with a small number of participants, so results may not apply broadly. Lidocaine is generally safe but can cause side effects like dizziness or heart issues.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Illnois at Chicago
RECRUITINGChicago, Illinois, 60612, United States
Contact
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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