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New drug MDX2001 tested in 285 patients with advanced cancers

NCT ID NCT06239194

Recruiting now Disease control Sponsor: ModeX Therapeutics, An OPKO Health Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called MDX2001 in people with advanced solid tumors that have spread. The main goals are to check the drug's safety and see if it can shrink tumors. About 285 adults with various cancers like lung, breast, or colon cancer will take part. This is an early-stage trial, so the focus is on finding the right dose and understanding side effects, not on a cure.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms breast cancer breast neoplasm cervical cancer colon carcinoma colonic neoplasm endometrial cancer endometrium neoplasm esophageal cancer Esophageal Neoplasms gastric cancer gastric neoplasm gastroesophageal cancer head and neck cancer Head and Neck Neoplasms hepatocellular carcinoma kidney cancer Liver Neoplasms malignant pancreatic neoplasm neoplasm non-small cell lung carcinoma pancreatic neoplasm pediatric hepatocellular carcinoma prostate cancer rectal cancer rectal neoplasm renal carcinoma thyroid cancer Thyroid Neoplasms Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BILIARY TRACT CANCER BREAST CANCER CERVICAL CANCER COLON CANCER ENDOMETRIAL CANCER ESOPHAGEAL CANCER GASTRIC CANCER GASTROESOPHAGEAL CANCER HEAD AND NECK CANCER HEPATOCELLULAR CANCER NON-SMALL CELL LUNG CANCER PANCREATIC CANCER PROSTATE CANCER RECTAL CANCER RENAL CANCER THYROID CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NEXT Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarah Cannon Research Institute

    RECRUITING

    Denver, Colorado, 80218, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sylvester Comprehensive Cancer Center - University of Miami Health System

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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