RENAL CANCER

This study is testing a new medicine called PF-08634404 for adults with advanced kidney cancer that has spread. Researchers want to see if the medicine is safe and effective when given alone or with other cancer drugs. The study is recruiting 224 adults who haven't received any t…

This study is observing whether a precise, high-dose radiation treatment can control primary kidney cancer in patients who are not candidates for surgery. It involves 53 adults with early-stage kidney cancer who are medically inoperable, at high surgical risk, or have declined su…

This study is testing a new radiation therapy approach that uses MRI scans during treatment to adjust radiation beams in real time. Researchers want to see if this method can better target tumors while sparing healthy tissue in patients with various cancers including pancreatic, …

This is the first study in people to test a new drug called NXP900 for advanced solid tumors. The main goals are to find a safe dose and see how the body processes the drug. The study will also look for early signs that the drug can shrink tumors, especially in cancers with speci…

This study is testing a new robotic surgery technique for removing small kidney tumors. The goal is to avoid clamping the main blood supply and using traditional stitches, which may help preserve more healthy kidney tissue and function after surgery. Researchers will enroll 190 p…

This study is testing a new three-drug combination for people with advanced kidney cancer that has spread. It aims to see if adding a new drug called BL-B01D1 to standard treatments can better shrink tumors and control the disease. The trial will enroll about 260 patients to meas…

This study aims to find out if women aged 50 and older who have blood in their urine from a sudden bladder infection need to go through the full set of tests to check for cancer. Researchers will follow 300 women for a year after they get standard tests like a bladder scope and a…

This study is testing a new type of imaging scan called a 68Ga-PSMA PET scan to see if it's better than standard CT scans at finding where advanced kidney cancer has spread. Researchers will enroll 300 adults with advanced kidney cancer to compare the two scans. The goal is to se…

This study is testing a new type of CT scanner to see if it can provide clearer, more detailed images during certain cancer procedures. It will involve about 30 adults with liver or kidney cancer who are already scheduled for a specific treatment. The goal is to see if this new i…

This study is testing a new blood test designed to detect many types of cancer early, before symptoms appear. It will involve 7,000 people, both with and without cancer, to see if the test can accurately spot cancer signals and identify where in the body the cancer started. The t…

This study aims to find the best way to manage pain and improve recovery after robotic surgery on the kidneys or ureters. It will compare two methods: a single spinal injection of pain medication given before surgery versus a continuous intravenous (IV) drip of a different medica…

This study is testing if common anti-inflammatory painkillers (like ibuprofen) can effectively manage pain after robotic kidney cancer surgery, with the goal of reducing the need for stronger opioid medications. It will involve 110 adults undergoing this specific surgery at the U…

This study aims to understand the inherited genetic factors that cause lymphoma, leukemia, and related cancers within families. Researchers are recruiting individuals and their family members who have a personal or family history of these diseases. The main goal is to collect DNA…

This study is testing a new type of PET scan that uses a special tracer called 64Cu-GRIP B. The goal is to see if this scan can safely detect a marker of immune system activity (granzyme B) in tumors of patients with advanced cancers, including prostate, kidney, and bladder cance…

This study aims to understand and improve how hospitals around the world treat patients who are urgently admitted with blood in their urine (hematuria). Researchers will observe the care of about 1,050 adult patients to see how different treatment approaches affect hospital stay …

This study is creating a large registry of DNA and health information from people with kidney cancer, their family members, and healthy volunteers. The goal is to collect data to help researchers understand the genetic factors involved in kidney cancer. This knowledge could lead …

This study is testing a new decision aid tool designed to help patients with small kidney tumors. The tool provides personalized information about treatment benefits and risks to support better conversations with doctors. Researchers want to see if using this tool improves patien…

This study is testing whether a short educational video can be a good alternative to standard genetic counseling for patients with certain cancers. Researchers want to see if the video helps people understand their risk for hereditary cancers and makes genetic testing information…

This study aims to understand how major surgeries for bladder, prostate, and kidney cancers, as well as procedures for kidney stones, affect patients' ability to return to their jobs and their overall quality of life. Researchers will survey 2000 adult patients in Poland about th…

This study collects blood, urine, and tissue samples from people with or suspected of having cancers of the kidney, bladder, prostate, and other urinary system cancers. The samples are stored in a tissue bank and used for research to understand the genetic causes of these cancers…

This study aims to collect and store blood, tumor, and tissue samples from children and adults with cancer to create a large research repository. The goal is to help scientists better understand cancer biology by studying these samples in the lab. Participants provide samples onl…