CERVICAL CANCER

This early-stage trial tests a new vaccine called PVX7 in 32 women with advanced cervical cancer who have finished their main treatment (surgery, radiation, or chemo). The goal is to see if the vaccine is safe and can boost the body's immune response against HPV, the virus that c…

This early-phase trial tests a new drug, ASTX660, combined with the immunotherapy pembrolizumab in people with advanced solid tumours, including cervical and triple-negative breast cancer. The goal is to see if blocking certain proteins can make cancer cells die in a way that tri…

This study tests a new drug called GI-101, either alone or with pembrolizumab or lenvatinib, in people with advanced solid tumors (cancers that have spread). The goal is to see if it is safe and works against the cancer. About 317 adults with certain cancers like lung, kidney, or…

This study tests a combination of two drugs, pembrolizumab and lenvatinib, in people with advanced cervical cancer that has not responded to previous treatment. The goal is to see if this combination can shrink tumors or slow cancer growth. About 35 participants will receive the …

This study tests whether adding a vitamin A-like drug (ATRA) to a platelet-boosting medication (romiplostim N01) works better than the platelet drug alone for cancer survivors whose platelet counts stay low after chemotherapy. About 220 adults with gynecologic, breast, or lung ca…

This study tests a new drug called TER-2013 in people with advanced solid tumors (like breast, endometrial, ovarian, lung, head and neck, esophageal, or cervical cancer) that have specific changes in the AKT/PI3K/PTEN pathway. The goal is to see if the drug is safe and shrinks tu…

This study tests a new immunotherapy for people with advanced HPV-related cancers (cervical, throat, anal, and others). Participants receive specially engineered immune cells designed to attack HPV-infected tumor cells, along with chemotherapy and a drug to boost cell activity. T…

This study looks at how well the drug T-DXd works in adults with advanced HER2-positive solid tumors that have spread and are not responding to other treatments. About 100 people will be followed to see if their tumors shrink and how long that lasts. The goal is to provide a trea…

This early-stage study tests a new treatment called CD70-targeted CAR-T cells in people with advanced solid tumors, including kidney, lung, and ovarian cancers. The therapy uses a patient's own immune cells, modified to recognize and attack cancer cells that have a specific marke…

This early-phase study tests a new drug called BL-B01D1 in people with advanced lung cancer or other solid tumors that have spread or cannot be removed. The main goals are to check the drug's safety and find the best dose. About 470 adults will take part to see if the drug can he…

This study tests a new drug called CNSI-Fe(II), which is injected directly into tumors. It uses iron to trigger a type of cell death called ferroptosis, aiming to control or shrink advanced solid tumors like lung, pancreas, and colorectal cancers. The study involves 54 adults who…

This study tests whether adding the drug serplulimab to standard chemoradiotherapy can help control locally advanced cervical cancer. It involves 216 women who have not yet been treated. The main goal is to see if the combination delays cancer growth or improves survival.

This early-stage study tests a new drug called STRO-004 in about 200 adults with advanced solid tumors (like lung, colon, or pancreatic cancer) that have not responded to standard treatments. The study has three parts: finding a safe dose of STRO-004 alone, testing that dose in m…

This study tests whether combining two drugs, lenvatinib and pembrolizumab, can slow tumor growth in people with cervical cancer that has spread or come back. About 30 adults with certain types of cervical cancer will receive the treatment. The goal is to see if the combination h…

This study tests a drug called ivonescimab in 50 people with advanced endometrial or cervical cancer that has worsened after standard chemotherapy. The drug targets two proteins (PD1 and VEGF) to help the immune system fight the cancer. The main goal is to see if the drug shrinks…

This study tests a shorter course of radiation therapy combined with chemotherapy for cervical cancer. Normally, treatment takes 7-8 weeks, but this approach aims to finish in less time while still being effective. The trial includes 34 adults with advanced cervical cancer and wi…

This study tests a combination of two drugs, Sac-TMT and QL1706, in people with cervical cancer that has come back or spread. The goal is to see if the combo can shrink tumors and improve survival. About 89 women with certain types of cervical cancer will take part.

This study compares proton therapy to standard photon therapy for cervical cancer patients who need radiation to a large area. The goal is to see if proton therapy can prevent a severe drop in immune cells (lymphopenia) and reduce side effects. About 44 adults with advanced cervi…

This early-phase study tests an experimental oral drug, RGT-490, in adults with advanced solid tumors (including breast, ovarian, and endometrial cancers) that have a specific genetic change called PIK3CA. The main goals are to check the drug's safety, find the right dose, and se…

This study tests different strategies to help people in Botswana start cervical cancer treatment sooner after diagnosis. Researchers will enroll 610 women with newly diagnosed invasive cervical cancer to see which approaches work best. The goal is to improve timely access to care…

This study tests a new drug, BMS-986340, alone or with other cancer treatments in people with advanced solid tumors that have not responded to standard therapy. The main goal is to find safe doses and check for side effects. About 949 adults with various cancers like lung, breast…

This study tests a new drug, PRGN-2009, combined with pembrolizumab in 24 adults whose recurrent or metastatic cervical cancer no longer responds to pembrolizumab alone. The goal is to see if the combination can shrink tumors or stop them from growing. Participants must have HPV-…

This phase 3 trial tests whether adding the targeted drug sacituzumab tirumotecan to standard immunotherapy (pembrolizumab) and a blood-vessel blocker (bevacizumab) helps people with metastatic cervical cancer live longer or keep their cancer from growing. About 1,000 participant…

This early-stage study tests a modified virus (KD01) designed to infect and kill cancer cells in women with cervical or endometrial cancer. Phase I includes patients who have exhausted other treatments; Phase II focuses on younger women who wish to preserve fertility. The goal is…

This study tests a drug called MGD019 to see if it can help control advanced cervical cancer in people who haven't had treatment yet. About 40 adults with cancer that has spread or come back will receive the drug. The main goal is to see if it helps them live longer.

This study tests a new drug, MK-2870, against standard treatments for people with cervical cancer that has come back or spread. About 686 participants whose cancer worsened after initial therapy will receive either MK-2870 or a doctor-chosen treatment. The main goal is to see if …

This early-phase study tests a new experimental treatment called VET3-TGI, a virus designed to attack cancer cells. It is given alone or with an immunotherapy drug (atezolizumab) to about 60 adults with advanced solid tumors that have not responded to standard treatments. The mai…

This study tests a new radiation method for people with cervical cancer or pelvic cancer that has come back. It is for those who cannot get standard brachytherapy because of unusual anatomy or large tumors. The goal is to see if this technique can control the cancer in the treate…

This early-phase trial tests a new drug called MDX2001 in people with advanced solid tumors that have spread. The main goals are to check the drug's safety and see if it can shrink tumors. About 285 adults with various cancers like lung, breast, or colon cancer will take part.

This study tests whether the drug belzutifan can shrink or control certain gynecologic cancers (like ovarian, endometrial, cervical, vaginal, or vulvar) that have come back or not gone away. About 32 adults with clear cell carcinoma will receive belzutifan pills. The main goal is…

This study tests whether a newer, more precise type of radiation (online adaptive radiotherapy) can reduce side effects and better control cervical cancer compared to standard image-guided radiotherapy. About 124 women with advanced cervical cancer will receive either the new or …

This study tests a new drug called LY4052031 in people with advanced or spreading solid tumors, including bladder, breast, lung, and other cancers. The goal is to see if the drug is safe and works against these cancers. About 420 participants will take part, and the study will la…

This study tests whether giving a single dose of specially engineered immune cells (E7 TCR-T cells) before standard treatment (chemoradiation or surgery) can shrink or eliminate tumors in people with advanced HPV-related cancers. About 15 participants will have their own T cells …

This study tests an experimental drug called YL202 in about 100 adults with advanced solid tumors, including lung, colorectal, and cervical cancers that have not responded to other treatments. The main goal is to see if YL202 can shrink tumors. Participants will receive the drug …

This early-phase study tests an experimental pill called NX-1607 in adults with advanced cancers that have not responded to standard treatments. The drug aims to boost the body's immune system to fight tumors. The main goals are to check safety and see if the drug can shrink or c…

This study tests an experimental drug called patritumab deruxtecan in people with advanced solid tumors that have spread or cannot be removed. The trial includes 740 participants with 13 different cancer types, such as lung, breast, and prostate cancer. The goal is to see if the …

This study tests two drugs, VS-6766 and defactinib, in people with certain gynecological cancers that have come back. The goal is to see if the combination can shrink tumors and how safe it is. About 55 adults with specific gene mutations (RAS, BRAF, or NF1) will take part.

This study tests a new drug called KRC-01, injected directly into the tumor, combined with standard radiation therapy for people with locally advanced cervical cancer. The goal is to see if the combination is safe and helps shrink tumors. About 70 participants will take part, fir…

This study tests whether adding a targeted radiation boost to the main tumor can help shrink large cervical cancers before internal radiation therapy begins. About 17 adults with bulky squamous cell carcinoma of the cervix will receive the extra boost during their standard 5-6 we…

This study tests an experimental oral drug called NEO212 in people with certain brain tumors (astrocytoma, glioblastoma) or cancers that have spread to the brain. The goal is to find the safest dose and see if it helps control the disease. About 134 adults will take part across t…

This study tests an experimental drug called MT-4561 in people with advanced solid tumors (like lung, breast, or pancreatic cancer) who have run out of standard options. The goal is to find a safe dose and see if the drug can shrink tumors. About 27 adults will take part in this …

This study tests a new drug called volrustomig, either alone or with chemotherapy, in people with advanced cervical, head and neck, esophageal, or mesothelioma cancers that have spread. The goal is to see if the drug can shrink tumors and control the disease. About 257 adults wit…

This study is testing a new drug, enzelkitug, for people with advanced solid tumors that have spread or cannot be removed by surgery. The trial includes many cancer types like lung, head and neck, melanoma, breast, and others. The main goal is to check the drug's safety and find …

This study tests a new drug called KIVU-107 in people with advanced solid tumors that have stopped responding to standard treatments. The drug is designed to target and kill cancer cells while limiting harm to healthy cells. The main goals are to find the safest dose and check fo…

This study tests whether adding the immunotherapy drug camrelizumab to standard chemotherapy can help prevent cervical cancer from coming back after surgery. It is for patients whose cancer has spread to nearby lymph nodes. About 59 participants will receive the combination treat…

This study tests whether a shorter, higher-dose radiation schedule (hypofractionated) is as safe and effective as the standard longer schedule for women with locally advanced cervical cancer. About 278 women in Uganda will receive either the shorter or standard radiation, plus ch…

This study looks at whether surgically removing enlarged lymph nodes before standard chemoradiation can help people with stage IIICr cervical cancer live longer without the cancer growing. About 452 participants will be randomly assigned to either have lymph node removal followed…

This study tests a combination of two or three drugs (BL-B01D1, pembrolizumab, and possibly bevacizumab) in people whose cervical or endometrial cancer has come back or spread. The goal is to see if the treatment shrinks tumors or slows the disease. About 96 adults aged 18-75 wit…

This study tests two experimental drugs, BL-B01D1 and SI-B003, alone or together in 130 women with recurrent or metastatic cervical cancer that has not responded to standard treatments. The goal is to see if these drugs can shrink tumors or slow disease progression. Participants …

This study is testing a new robotic surgery system (Medtronic Hugo™) to see if it is safe and works well for hysterectomy. About 70 adult women with conditions like fibroids, endometriosis, or certain cancers will take part. The main goal is to see if the surgery can be completed…

This study is testing an experimental drug called MGC026 in about 250 adults with advanced solid tumors that have not responded to other treatments. The main goals are to check the drug's safety and find the right dose. Participants receive the drug by IV and are closely monitore…

This early-phase study tests a new drug called NRM-823, alone or with an immunotherapy, in 150 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. The study includes several cancer types lik…

This study tests whether combining two drugs, ZG005 and gecacitinib (with or without bevacizumab), is safe and can shrink tumors in people with advanced cervical cancer. About 120 women aged 18–75 whose cancer has spread or returned will take part. The goal is to find the best do…

This early-phase study tests a new treatment called 177LuBetaBart for people with advanced solid tumors that have stopped responding to standard therapies. The treatment combines a targeting antibody with a radioactive particle to deliver radiation directly to cancer cells. The s…

This early-phase study tests an experimental drug called BL-M07D1 in 280 adults with advanced solid tumors that have the HER2 protein. The goal is to see if the drug is safe and can shrink tumors in cancers like breast, lung, stomach, and ovarian cancer. Participants must have tr…

This study tests whether a non-invasive physical plasma treatment can clear HPV infections from the cervix. About 50 adults with HPV will receive the treatment, and researchers will check if the virus is gone afterward. The goal is to find a new way to prevent cervical cancer cau…

This study tests whether adding a drug called tarlatamab to standard radiation therapy is safe and effective for cancers that have a protein called DLL3, such as certain lung cancers, melanomas, and bladder cancers. About 30 adults with advanced or returning cancers will receive …

This early-stage study tests a new injection called TI-0093 in 12 adults with HPV-16 positive cancers (like head, neck, or cervical cancer) that returned or spread. The main goals are to check safety, find the best dose, and see how the body responds. It is not a cure but aims to…

This early-phase study tests a new drug called DR-0202 in people with advanced solid tumors (like breast, lung, or pancreatic cancer) that have stopped responding to standard treatments. The main goal is to check the drug's safety and find the right dose. About 96 participants wi…

This study tests a new drug called HLX43 in people with advanced cervical or ovarian cancer that came back or spread after standard first treatment. The drug targets a protein on cancer cells to deliver a toxin directly. About 190 adults will receive the drug to see if it shrinks…

This study tests a new drug that delivers radiation directly to cancer cells with a specific marker (GRPR). It is for adults with advanced cancers like prostate, breast, lung, or colon cancer that have come back or spread. The main goal is to find a safe dose and check for side e…

This study tests a drug called sacituzumab govitecan in 20 people whose cervical cancer has returned or persisted after at least one prior treatment. The drug works like a guided missile, delivering chemotherapy directly to cancer cells. The main goal is to see how many patients'…

This study tests whether using MRI to guide brachytherapy (internal radiation) can better target tumors and reduce radiation exposure to nearby organs like the bladder and rectum. About 54 adults with cervical, uterine, vaginal, vulvar, or bladder cancer will receive treatment in…

This study compares two new technologies for detecting cervical cancer in Mozambique: a quick HPV test and a special imaging system. About 678 women aged 25-49 who have had an abnormal screening result will participate. The goal is to see if these tools are as accurate as current…

This study looks at whether giving women a simple at-home kit to test for HPV (the virus that can cause cervical cancer) makes it easier for those who are overdue for screening to get tested. About 100 women aged 25-65 who haven't had a Pap smear in 3 years will receive a self-co…

This study is testing a new type of PET scan that uses a special tracer to find a protein called Trop2 on cancer cells. The goal is to see if this scan can detect and monitor many types of solid tumors more accurately than current methods. About 400 adults with or suspected of ha…

This study is testing a new way to detect cervical cancer using light instead of a traditional biopsy. Researchers are looking for unique light patterns (optical signatures) that can identify early abnormal cells. The study will involve 350 women who are already scheduled for a c…

This study is testing a new imaging agent called 18F-T2, which targets a protein (CAIX) found on many solid tumors. About 200 adults with cancers like kidney, bladder, colorectal, or lung cancer will receive a PET/CT scan using this agent. The goal is to see if it can find tumors…

This study aims to create a test that can find endometrial, ovarian, and cervical cancers by looking for specific DNA markers in vaginal fluid or blood. Researchers at Mayo Clinic will collect samples from over 3,000 women to see how well the test works. The goal is to make cance…

This study explores whether women from underserved communities can accurately collect their own samples to test for HPV, the virus that can cause cervical cancer. Researchers will compare results from two different self-collection kits to standard Pap smears. The goal is to make …

This study is testing a new blood test that looks for tiny pieces of HPV DNA shed by cancer cells. The goal is to see if this simple blood draw can tell the difference between pre-cancer and invasive cervical cancer, and help monitor patients during and after treatment. The study…

This study is testing a blood test that looks for DNA signals from 20 different cancers, including breast, lung, and colon cancer. Researchers want to see if the test can find cancer early, detect any cancer left after treatment, and catch a relapse before symptoms appear. About …

This study compares self-collected Pap smears to traditional doctor-collected ones for cervical cancer screening. About 250 women aged 21-65 in rural Alabama will participate. The goal is to see if self-sampling is accurate enough to boost screening rates in underserved communiti…

This study is testing a new, affordable way to screen for cervical cancer using artificial intelligence. It analyzes urine samples and cervical images to detect high-risk HPV and precancerous changes. The goal is to provide a one-stop screening and triage system that works in low…

This study is testing a handheld, AI-powered colposcope (called Pocket CARE) to see if it can accurately detect cervical pre-cancer in women who have tested positive for HPV. About 1,054 women in Kenya will use the device during a pelvic exam. The goal is to improve screening and…

This study checks how effective the HPV vaccine is at preventing cervical HPV infection in real-world conditions in Sikkim, India. Researchers will compare HPV infection rates in married women aged 18-22 before and 7 years after the vaccine program started. The goal is to give qu…

This study looks at how to better provide cervical cancer screening and treatment to women living with HIV in Nigeria. About 2,400 women will take part. The goal is to find the best way to combine cancer care with existing HIV services to prevent cervical cancer and improve healt…

This study tests whether a simple reminder from a general practitioner can encourage more women aged 25 to 65 to get screened for cervical cancer. In France, only about 59% of eligible women participate in the national screening program. The study will involve over 11,000 women i…

This study tests whether offering a self-sampling kit for HPV detection can increase cervical cancer screening among women who have not been screened in at least 3 years. About 15,000 women in the Czech Republic will be invited to collect their own sample at home. The goal is to …

This study aims to prevent unnecessary deaths from cervical cancer in Senegal by helping more women get screened early. Researchers will adapt a patient navigation program for both urban and rural areas, addressing barriers like stigma and misinformation. About 901 women and men …

This study tests a program that combines cervical cancer screening, nutrition education, protein supplements, and emotional support for women in India who have both HIV and HPV. The goal is to see if this approach can reduce persistent HPV infections, a key risk factor for cervic…

This study tests a new care strategy called DADA LINK to help more women in Kenya get screened for cervical cancer and receive treatment if needed. About 1,980 women aged 25-49 will take part. Clinics will use a mobile health platform and care coordinators to support screening an…

This study tests whether Reiki, a gentle hands-on therapy, can reduce anxiety and pain in people receiving brachytherapy (internal radiation) for gynecologic cancers like endometrial, cervical, vaginal, or vulvar cancer. About 70 participants will be randomly assigned to receive …

This early-phase study tests whether fecal microbiota transplantation (FMT) can safely reduce severe diarrhea or colon inflammation caused by immune-checkpoint inhibitors in people with genitourinary and other cancers. About 40 participants will receive FMT and be monitored for s…

This study compares a 1-week radiation schedule to a standard 6-8 week schedule for relieving pain in people with advanced cervical cancer that cannot be cured. The goal is to see if the shorter treatment provides faster and effective pain relief. About 230 participants will be e…

This study looks at possible eye-related side effects in people with cervical cancer that has returned or spread, who are being treated with the drug TIVDAK. About 100 participants will receive TIVDAK every three weeks and undergo regular eye exams before, during, and after treat…

This study is testing whether starting pelvic floor physical therapy soon after radiation treatment can reduce bowel and bladder control problems in women with cervical cancer. About 28 women will receive the therapy and be checked for incontinence three months later. The goal is…

This study tests a new way to deliver radiation for cervical cancer. Instead of using one fixed plan for weeks, an AI adjusts the radiation daily based on the tumor's position, and weekly MRI scans provide extra guidance. The goal is to reduce side effects like bladder and bowel …

This study tests a precise type of proton radiation given after surgery for cervical, uterine, or endometrial cancer. The goal is to see if it causes fewer bowel side effects than standard radiation. About 25 adults who need pelvic radiation after surgery will take part.

This study looks at whether using the Headspace mindfulness app before surgery or chemoradiation can help people with endometrial or cervical cancer use fewer opioid painkillers. About 120 participants will be randomly assigned to use the app or not. The goal is to see if mindful…

This study looks at whether changes in a blood marker called CRP can help predict how well immunotherapy works in women with advanced gynecological cancers (cervical, endometrial, ovarian, or vulvar). Researchers will follow 120 women receiving immunotherapy plus chemotherapy and…

This study is testing whether a newer type of scan, called PET/MRI, is better than the standard PET/CT scan at finding cancer that has spread to lymph nodes in people with cervical cancer. About 50 adults with stage IB2 to IVA cervical cancer will get both scans before treatment.…

This study is testing a mobile health tool called mSaada to help community health workers screen women for cervical cancer in western Kenya. Researchers will work with 6,000 women and health volunteers to see if the app makes screening easier and more effective. The goal is to fi…

This study looks at whether a simple blood test can find HPV DNA in people with HPV-related anal or cervical cancer who are getting radiation therapy. Researchers will take blood samples before, during, and after treatment to see if the virus's genetic material shows up and if it…

This study is testing a new device called the Calla introducer to see if women prefer it over the standard speculum during cervical cancer screening. Researchers will interview and survey about 305 healthy women aged 21-65 to gather their opinions. The goal is to improve the scre…

This study is testing whether liquid biopsies (blood tests that look for bits of HPV DNA) can help doctors monitor how well treatment is working for HPV-related cancers, like cervical and oropharyngeal cancer. Researchers will follow 480 people for up to 4 years, collecting sampl…

This study looks at how the amount and storage of a green dye (indocyanine green) affect its ability to find the first lymph nodes where cancer might spread in people with cervical, endometrial, or vulvar cancer. Researchers will test different doses and storage methods to see wh…

This study looks at whether offering cervical cancer screening together with family planning services helps more women get screened. About 14,600 women aged 30-49 or those living with HIV in two regions of Mozambique will take part. The goal is to see if combining these services …

This study is collecting blood and tumor samples from 1100 people with various cancers (like head and neck, ovarian, and lung cancer) to learn how immune cells called T cells behave. The goal is to understand why some cancers are better at hiding from the immune system. Participa…

This study explores whether a simple self-sampling kit for HPV can help screen for cervical cancer in women aged 30-60 in Zaporizhzhia, Ukraine, during the ongoing war. Participants collect their own sample at home or a clinic and send it for testing. The goal is to see if this a…

This study tests a program called CARES that provides advocacy, resources, education, and support to rural cancer patients. The goal is to see if it helps them start treatment sooner after diagnosis and finish it faster. The study will include 320 adults with solid tumors like lu…

This study is testing two new blood tests that look for HPV DNA and RNA to see how well cervical cancer responds to standard treatments like surgery, radiation, and chemotherapy. About 55 adults with HPV-related cervical cancer will give blood samples before and after treatment. …

This early-phase study is testing a new substance called RAD301 in 9 healthy volunteers and people with certain cancers (pancreatic, lung, esophageal, cervical, endometrial, or ovarian). The goal is to see how the body absorbs and handles the radiation from RAD301, and whether it…

This study tests whether artificial intelligence can help more women in the Occitanie region of France complete cervical cancer screening. Researchers will invite 3,000 women aged 30-65 who haven't had a Pap smear in 4 years to use an HPV self-sampling kit. The goal is to see if …

This study is testing whether HPV DNA found in blood and urine can be used to detect cervical cancer and track how well treatment is working. Researchers will collect samples from 30 women newly diagnosed with cervical cancer before and after their treatment. The goal is to see i…

This study tests a faster way to screen and treat cervical cancer in women living with HIV in the Dominican Republic. It compares same-day HPV testing and treatment to the usual care. The goal is to see if more women complete the full screening process, which could save lives.

This study looks at whether a special PET scan and a blood test for HPV can find leftover cancer cells in people with cervical cancer after they finish standard chemoradiation. About 64 adults with stage IB-IVA cervical cancer will join. The goal is to see how well these tests pr…

This study looks at whether peer-to-peer education and support can help more young people (ages 15-39) living with HIV get screened for cancer and stick with their cancer treatment. The study will enroll 4,100 participants in Zambia. The goal is to reduce cancer deaths in this gr…

This study looks at whether people with certain cancers prefer getting their immunotherapy (nivolumab or pembrolizumab) as a shot under the skin or as an IV drip. About 880 patients will try both methods and say which they like better. The goal is to understand patient preference…

This study is gathering tumor, blood, and plasma samples from over 1,000 people with certain cancers (ovarian, triple-negative breast, head and neck, cervical, vulva, and sarcoma). The goal is to find new biomarkers that link a tumor's genetic changes and the body's immune respon…

This study looks at the best times to send messages that encourage physical activity to older adults (65+) who have survived certain cancers and still have chronic pain. Researchers will track activity with a wearable device and ask participants to rate their pain four times a da…

This study aims to understand how the tumor's surroundings change during chemoradiotherapy for locally advanced cervical and pancreatic cancers. Researchers will collect tissue samples, blood, and imaging data from 60 participants before, during, and after treatment. The goal is …