Extra radiation boost shows promise for bulky cervical cancer
NCT ID NCT07435376
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing whether adding a precise radiation boost to standard treatment can shrink large cervical tumors more effectively. Seventeen participants with bulky squamous cell carcinoma will receive external radiation plus a targeted boost, followed by internal brachytherapy. The main goal is to see if the boost reduces tumor volume enough before brachytherapy, while also monitoring side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (intra-lesional boost IMRT and high-dose-rate brachytherapy)
What this could lead to
If successful, this approach could improve tumor shrinkage before brachytherapy, potentially leading to better local control and outcomes for patients with bulky cervical cancer.
What could go wrong
This is a small, early-phase trial with only 17 participants, so results may not apply broadly. The extra radiation could increase side effects, and it's unclear if it will improve long-term survival.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, Gyeonggi-do, 13620, South Korea