Seoul National University Bundang Hospital

This study compares two drugs, choline fenofibrate and policosanol, in 56 Korean adults with type 2 diabetes and high cholesterol who have early signs of artery plaque. The goal is to see if choline fenofibrate can reduce plaque buildup in the carotid artery, measured by 3D ultra…

This study compares two diabetes medications, enavogliflozin and pioglitazone, when added to standard metformin treatment. It includes 120 adults with type 2 diabetes whose blood sugar is not well controlled. The goal is to see which drug works better at lowering blood sugar and …

This study compares two medications, clopidogrel and cilostazol, to see if they can slow down the buildup of plaque in the neck arteries of people with type 2 diabetes. The goal is to prevent future heart attacks and strokes. About 120 adults with diabetes and early signs of arte…

This study looks at whether adding omega-3 to a common statin (atorvastatin) can better reduce plaque buildup in the neck arteries of people with type 2 diabetes and high cholesterol. About 105 adults will be randomly assigned to get either atorvastatin plus omega-3 or atorvastat…

This study compares two treatments for H. pylori infection, a common stomach bug. One uses a newer drug called tegoprazan, while the other uses a standard proton pump inhibitor. The trial will enroll 400 adults in South Korea, where antibiotic resistance makes treatment difficult…

This study compares two antibiotic treatments for H. pylori, a stomach infection. 600 adults will get either a 10-day standard treatment or a 7-day treatment tailored to their bacteria's drug resistance. The goal is to see which approach eradicates the infection more effectively.

This study tests whether giving a diuretic (furosemide) to reduce fluid buildup can better protect the kidneys from contrast dye damage compared to standard IV fluids. It involves 190 adults hospitalized with acute heart failure and moderate kidney problems who need a CT scan. Re…

This study looks at whether a special blood filter called oXiris helps people with septic shock and kidney failure survive. Researchers will review medical records of 360 adults in the ICU who needed continuous blood filtering. They will compare those who got the oXiris filter wi…

This phase 2 trial is testing whether adding a precise radiation boost to standard treatment can shrink large cervical tumors more effectively. Seventeen participants with bulky squamous cell carcinoma will receive external radiation plus a targeted boost, followed by internal br…

This study looks at whether hypothyroidism caused by immune checkpoint inhibitors (a type of cancer immunotherapy) can go away after stopping the immunotherapy. 107 adult cancer patients who developed hypothyroidism during treatment and are now off immunotherapy will gradually re…

This study tests whether giving levothyroxine (a thyroid hormone) to people with mild underactive thyroid before and after heart bypass surgery can lower the risk of serious heart problems like heart attack, stroke, or irregular heartbeat. About 338 adults will be randomly assign…

This study tests whether a natural extract from the hyacinth bean (EDL) can reduce stomach symptoms like pain, fullness, and burning in people with functional dyspepsia. About 100 adults will take EDL or a placebo daily for 12 weeks. Researchers will measure symptom changes using…

This study tests a smartphone app called Zenicom that provides personalized speech therapy exercises for people who have trouble speaking after a stroke (aphasia). Twenty adults with recent stroke and aphasia will either receive standard speech therapy alone or standard therapy p…

This study enrolls 1,000 adults with advanced solid tumors that have progressed after standard treatment. Researchers will use genetic tests to match patients to specific drugs, like Alectinib or Atezolizumab, based on their tumor's gene changes. The goal is to see if this person…

This study is tracking 1,400 people with colorectal cancer to see how the disease behaves differently based on age and sex. Researchers are looking at survival rates and whether the cancer comes back, focusing on molecular profiles and sex hormone receptors. The goal is to better…

This study aims to identify biological markers that can predict how patients with inflammatory bowel disease (IBD) will respond to a type of medication called TNF-alpha inhibitors. Researchers will collect blood and tissue samples from 100 adults, including healthy controls and I…

This observational study is looking at whether the brain's ability to use oxygen during surgery is linked to postoperative delirium in adults aged 65 and older. Researchers will use a non-invasive forehead sensor to measure brain oxygen levels during routine laparoscopic surgery …

This study tests how different frequencies of electrical stimulation affect tongue muscles in 28 adults at high risk for sleep apnea. During a single visit, participants receive five different stimulation frequencies in random order. Researchers measure changes in tongue muscle t…

This study looks at the gut bacteria of older adults with sarcopenia (age-related muscle loss) and compares them to healthy older and young adults. The goal is to find differences that could help create probiotics to treat sarcopenia. Researchers will enroll 150 people aged 65-90…