Seoul National University Bundang Hospital

This study compares two diabetes medications, enavogliflozin and pioglitazone, when added to metformin (with or without another drug) in 120 adults with type 2 diabetes. The goal is to see which drug better controls blood sugar and improves other health measures like weight, body…

This study tests whether choline fenofibrate can reduce plaque buildup in the carotid arteries of people with type 2 diabetes and mixed high cholesterol. About 56 participants will receive either choline fenofibrate or a comparison drug (policosanol) for several months. The main …

This study compares two medications, clopidogrel and cilostazol, to see which better slows the thickening of neck arteries in people with type 2 diabetes. About 120 adults with diabetes and early signs of artery disease will take one of the drugs for a period. The goal is to find…

This study tests whether adding a targeted radiation boost to the main tumor can help shrink large cervical cancers before internal radiation therapy begins. About 17 adults with bulky squamous cell carcinoma of the cervix will receive the extra boost during their standard 5-6 we…

This study looks at whether adding omega-3 (fish oil) to a common cholesterol-lowering statin can reduce plaque buildup in the carotid arteries of people with type 2 diabetes and high cholesterol. About 105 adults will be randomly assigned to receive either atorvastatin plus omeg…

This study looks at whether giving a thyroid hormone pill (levothyroxine) to people with mild thyroid issues before heart bypass surgery can lower the risk of heart problems like heart attack, stroke, or irregular heartbeat. About 338 adults will be randomly assigned to receive t…

This study compares two 10-day treatments for Helicobacter pylori infection, a stomach bug that can cause ulcers and cancer. Researchers want to see if a newer drug (tegoprazan) works better than standard proton pump inhibitors when combined with antibiotics. The trial will enrol…

This study looks at whether a special filter called oXiris helps people with septic shock and kidney failure survive. Researchers will compare patients who got the oXiris filter with those who got standard filters during blood cleaning. The goal is to see if the oXiris filter red…

This study looks at whether hypothyroidism caused by immune checkpoint inhibitors (a type of cancer immunotherapy) can get better after stopping the immunotherapy. Researchers want to see how many patients can safely stop taking thyroid hormone medication. The study involves 107 …

This study compares two ways to treat H. pylori, a stomach infection that can cause ulcers. One group gets a 10-day standard antibiotic sequence; the other gets a 7-day treatment tailored to the specific bacteria's drug resistance. The goal is to see which approach clears the inf…

This study looks at two ways to prevent kidney damage from contrast dye used in CT scans for people hospitalized with acute heart failure and moderate kidney problems. One group gets standard IV fluids, the other gets a medication to reduce fluid buildup. The goal is to see which…

This study tests whether a natural extract called EDL (from the Dolichos lablab plant) can reduce stomach discomfort in adults with functional dyspepsia—a condition where the stomach feels upset without a clear medical cause. About 100 participants will take EDL or a placebo dail…

This study tests a digital speech therapy app called Zenicom for people who have trouble speaking after a stroke. Twenty adults with aphasia (language difficulty) will either do standard speech therapy alone or add the app for two weeks. The goal is to see if the app safely impro…

This study looks at the gut bacteria of older adults with sarcopenia (age-related muscle loss) and compares them to healthy older and young adults. Researchers want to find differences that could help create probiotics to treat sarcopenia. The study involves 150 participants and …

This study looks at how different speeds of mild electrical pulses to the tongue and chin muscles affect muscle size, strength, and comfort in 28 adults at high risk for sleep apnea. Participants receive five different stimulation frequencies in one visit, and researchers measure…

This study looks at how colon cancer behaves differently in younger patients compared to older ones, and how sex and genetics play a role. Researchers will follow 1,400 people diagnosed with colorectal cancer to track survival and recurrence. The goal is to better understand the …

This study aims to find biological markers in blood and tissue samples that can predict how patients with inflammatory bowel disease (IBD) will respond to a type of medication called TNF-alpha inhibitors. Researchers will compare samples from 100 adults, including healthy control…

This study watches 80 adults aged 65 and older having planned laparoscopic surgery. It uses a non-invasive forehead sensor to measure brain oxygen use during surgery. The goal is to see if a reduced ability to use oxygen is linked to postoperative delirium (sudden confusion) in t…