Gene-Guided cancer therapy: a new hope for advanced tumors?
NCT ID NCT05525858
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study enrolls 1,000 adults with advanced solid tumors that have progressed after standard treatment. Researchers will use genetic tests to match patients to specific drugs, like Alectinib or Atezolizumab, based on their tumor's gene changes. The goal is to see if this personalized approach is feasible and helps control the cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Alectinib, Atezolizumab, and other targeted/immunotherapies based on genomic alterations
What this could lead to
If successful, this could show that using genetic tests to choose cancer treatments improves outcomes for people with advanced solid tumors who have run out of standard options.
What could go wrong
This is an early-stage feasibility study, not a large confirmatory trial. The treatments are used outside their approved indications, so benefits are uncertain and there may be unexpected side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ajou University Hospital
RECRUITINGSuwon, South Korea
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Asan Medical Center
RECRUITINGSeoul, South Korea
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Cha University Bundang Medical Center
RECRUITINGSeongnam, South Korea
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Chonnam National University Hwasun Hospital
RECRUITINGHwasun, South Korea
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Chung-ang University Hospital
RECRUITINGSeoul, South Korea
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Chungbuk National University Hospital
RECRUITINGChungju, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Dong-A University Hospital
RECRUITINGPusan, South Korea
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Ewha womans university Mokdong Hospital
RECRUITINGSeoul, South Korea
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Gachon University Gil Medical Center
RECRUITINGIncheon, South Korea
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Gangbuk Samsung Hospital
RECRUITINGSeoul, South Korea
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Gyeongsang National University Hospital
RECRUITINGJinju, South Korea
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Hanyang University Hospital
TERMINATEDSeoul, South Korea
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Jeonbuk National University Hospital
RECRUITINGJeonju, South Korea
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Keimyung University Dongsan Hospital
RECRUITINGDaegu, South Korea
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Korea University Anam Hospital
RECRUITINGSeoul, South Korea
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Korea University Guro Hospital
RECRUITINGSeoul, South Korea
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Kyungpook National University Chilgok Hospital
RECRUITINGDaegu, South Korea
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National Cancer Center
RECRUITINGGoyang, South Korea
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Pusan National University Yangsan Hospital
RECRUITINGYangsan, South Korea
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Samsung Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Bundang Hospital
RECRUITINGSeongnam, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, South Korea
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Soonchunhyang University Hospital Bucheon
RECRUITINGBucheon-si, South Korea
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The Catholic University of Korea, Incheon St. Mary's Hospital
RECRUITINGIncheon, South Korea
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The Catholic University of Korea, ST. Vincent's Hospital
RECRUITINGSuwon, South Korea
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The Catholic University of Korea, Seoul ST. Mary's Hospital
RECRUITINGSeoul, South Korea
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The Catholic University of Korea, Yeouido St. Mary's Hospital
RECRUITINGSeoul, South Korea
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Wonju Severance Christian Hospital
TERMINATEDWŏnju, South Korea
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Yeungnam University Medical Center
RECRUITINGDaegu, South Korea
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Yonsei Cancer Hospital
RECRUITINGSeoul, South Korea
Contact