Can a Tumor's DNA guide better cancer care for kids?
NCT ID NCT05691608
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study looks at whether analyzing the genetic makeup of tumors from children and young adults with cancer that has returned or not responded to treatment can help doctors choose more personalized therapies. Participants provide tumor and blood samples, which are sequenced to find specific genetic changes. A team of experts then discusses these results to recommend targeted treatment options. The goal is to improve survival and introduce new treatment strategies for advanced pediatric cancers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tumor biopsy and blood sample for molecular profiling
- What this could lead to
- If successful, this could help match more children with advanced cancer to targeted treatments based on their tumor's unique genetic makeup, potentially improving outcomes.
- What could go wrong
- This is an observational profiling study, not a treatment trial, so it may not directly benefit participants. The success depends on whether identified genetic changes can be matched to available drugs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHRU Morvan
RECRUITINGBrest, 29200, France
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CHRU Nancy Hôpital Enfants
RECRUITINGVandœuvre-lès-Nancy, 54500, France
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CHU Amiens-Picardie
RECRUITINGAmiens, France, 80054, France
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CHU Angers
RECRUITINGAngers, 49933 Cedex 9, France
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CHU Arnaud de Villeneuve
RECRUITINGMontpellier, 34295, France
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CHU Besançon
RECRUITINGBesançon, 25030, France
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CHU Dijon François Mitterand
RECRUITINGDijon, 21079, France
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CHU Estaing
RECRUITINGClermont-Ferrand, 63000, France
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CHU Grenoble Alpes
RECRUITINGGrenoble, 38043, France
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CHU La Timone
RECRUITINGMarseille, 13005, France
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CHU Nantes
RECRUITINGNantes, 44093, France
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CHU Pellegrin
RECRUITINGBordeaux, 33076, France
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CHU Poitiers
RECRUITINGPoitiers, 86022 Cedex, France
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CHU Reims- Hôpital Américain
RECRUITINGReims, 51100, France
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CHU Rennes Hôpital Sud
RECRUITINGRennes, 35203, France
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CHU Saint Etienne
RECRUITINGSaint-Etienne, France, 42270, France
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CHU de Caen
RECRUITINGCaen, 14000, France
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CHU de La Réunion site nord
RECRUITINGSaint-Denis, 97400, France
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CHU de Nice
RECRUITINGNice, 06202, France
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CHU de Rouen
RECRUITINGRouen, 76000, France
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Centre Oscar Lambret
RECRUITINGLille, 59020, France
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Chu Limoges
RECRUITINGLimoges, 87000, France
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Gustave Roussy
RECRUITINGParis, Villejuif, 94800, France
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Hopital Armand Trousseau
RECRUITINGParis, France, 75012, France
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Hôpital Clocheville
RECRUITINGTours, 37000, France
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Hôpital de Hautepierre
RECRUITINGStrasbourg, 67200, France
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Hôpital des Enfants - CHU de Toulouse
RECRUITINGToulouse, 31059, France
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IHOP
RECRUITINGLyon, 69373, France
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Institut Curie
RECRUITINGParis, 75005, France
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