Surgery before standard treatment may extend life in cervical cancer
NCT ID NCT04555226
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study is testing whether surgically removing enlarged lymph nodes in the pelvis and abdomen before standard chemoradiation can help people with stage IIICr cervical cancer live longer without the cancer growing. About 452 participants will be randomly assigned to either have the lymph node surgery followed by chemoradiation, or chemoradiation alone. The goal is to see if the surgery improves progression-free and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lymph node dissection (surgery)
What this could lead to
If successful, this could show that removing enlarged lymph nodes before standard chemoradiation helps people with advanced cervical cancer live longer without the disease progressing.
What could go wrong
This is a relatively early-stage trial (Phase not specified) with a moderate size of 452 participants. The surgery itself carries risks like infection, bleeding, or nerve damage, and it may not improve survival compared to chemoradiation alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chongqing Cancer Hospital
RECRUITINGChongqing, Chongqing Municipality, 400030, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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