Surgery before standard treatment may extend life in cervical cancer
NCT ID NCT04555226
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study is testing whether surgically removing enlarged lymph nodes in the pelvis and abdomen before standard chemoradiation can help people with stage IIICr cervical cancer live longer without the cancer growing. About 452 participants will be randomly assigned to either have the lymph node surgery followed by chemoradiation, or chemoradiation alone. The goal is to see if the surgery improves progression-free and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lymph node dissection (surgery)
- What this could lead to
- If successful, this could show that removing enlarged lymph nodes before standard chemoradiation helps people with advanced cervical cancer live longer without the disease progressing.
- What could go wrong
- This is a relatively early-stage trial (Phase not specified) with a moderate size of 452 participants. The surgery itself carries risks like infection, bleeding, or nerve damage, and it may not improve survival compared to chemoradiation alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CERVICAL CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chongqing Cancer Hospital
RECRUITINGChongqing, Chongqing Municipality, 400030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug combo revive Immunotherapy's power against resistant tumors?
- Can an antiviral make radiation more effective against cervical cancer?
- A One-Two punch against cervical cancer: testing plus vaccination in HIV-Positive women
- Can a Two-Antibody combo outsmart advanced cancer?
- Can robotic surgery match open surgery in beating cervical cancer?
- Blood test clues could sharpen cervical cancer treatment