CERVICAL CANCER

This large Phase 3 trial is testing a new 9-valent HPV vaccine designed to protect against nine types of human papillomavirus. It aims to prevent cervical cancer, precancerous lesions, and genital warts. The study compares the new vaccine's effectiveness and safety against an exi…

This large, late-stage study is testing whether adding a new immunotherapy drug called AK104 to standard chemotherapy helps women with advanced cervical cancer that has returned or spread. The goal is to see if this combination can better control the cancer, helping patients live…

This study is testing whether adding an experimental drug called Q702 to an existing immunotherapy (pembrolizumab) can help control advanced cancers that have stopped responding to previous treatments. The trial will enroll 120 people with advanced esophageal, stomach, liver, or …

This early-phase trial is testing a new therapeutic HPV vaccine, given alone or combined with an immunotherapy drug called M7824, in people with cancers linked to HPV. The main goals are to find a safe dose and see if the treatments can stimulate the body's immune system to bette…

This early-stage study is testing a new drug called IMGN151 in patients with recurrent gynecologic cancers that have returned after previous treatments. The main goals are to determine the safest dose, understand how the drug behaves in the body, and see if it shows any early sig…

This is the first human study testing the safety of an experimental drug called AB598 in people with advanced cancers. The trial will enroll 40 participants with various cancers including lung, stomach, bladder, and breast cancer to determine safe dosage levels and monitor side e…

This study tests whether personalized phone counseling and text messages help cervical cancer survivors quit smoking and stay smoke-free for two years. Researchers are comparing this approach to standard quitline support. The study involves 360 participants in Florida who have a …

This study tested an immunotherapy drug called pembrolizumab in people with many different types of advanced solid tumors that had stopped responding to standard treatments. The main goal was to see if the drug could shrink tumors and to identify biological markers that might pre…

This large, late-stage study is comparing a new two-drug combination (camrelizumab and famitinib) against standard platinum-based chemotherapy for women with recurrent or metastatic cervical cancer. The main goals are to see if the new combination helps patients live longer witho…

This study is testing a new combination of immune-boosting drugs for people with advanced cancers whose disease has progressed after treatment with standard immunotherapies like pembrolizumab or nivolumab. It aims to see if adding a drug called NAI to other treatments can help sh…

This study is testing whether a community program called Potlako+ can help people with possible cancer symptoms get diagnosed and treated faster. The program involves educating communities about cancer warning signs and providing patient navigators to guide people through the hea…

This study is testing whether a combination of two immunotherapy drugs, dostarlimab and cobolimab, can help control advanced cervical cancer that has spread or come back. It will involve about 66 adults whose cancer has progressed after standard platinum-based chemotherapy. The m…

This study is testing a new combination of three immunotherapy drugs for people with advanced cancers that have not responded well to standard treatments. It focuses on cancers linked to HPV (like cervical, throat, and anal cancers) and certain colon cancers. The main goals are t…

This is an early-stage study to find a safe dose of a new immunotherapy drug called HFB200301. It is being tested alone and in combination with an existing drug (tislelizumab) in adults with advanced solid tumors who have already tried other treatments. The main goal is to see ho…

This early-stage study is testing a new drug called RNDO-564, both by itself and combined with an existing immunotherapy (pembrolizumab), in adults with advanced cancers that have stopped responding to standard treatments. The main goals are to find safe doses and see how the bod…

This study is testing a new oral drug called AZD5305 to see if it is safe and can help control advanced cancers. It is being tested alone and in combination with other cancer medicines in over 700 patients with various hard-to-treat solid tumors. The main goals are to find the ri…

This study is testing whether a combination of two drugs, zimberelimab and lenvatinib, can help control advanced cervical cancer that has continued to grow despite prior immunotherapy. It aims to see if this combination is safe and effective for up to 30 women whose cancer has pr…

This trial is testing a new drug called tisotumab vedotin for women with advanced cervical cancer that has come back or spread. The study will see how safe the drug is when given alone or combined with other cancer medicines, and if it helps shrink tumors. It is for women who hav…

This early-stage study is testing the safety of a new, personalized cell therapy for people with advanced solid tumors that have stopped responding to standard treatments. Doctors collect a patient's own immune cells, genetically modify them to better recognize and attack their s…

This early-stage trial is testing a new antibody drug called acasunlimab (GEN1046) for people with advanced solid tumors. The study first aims to find safe doses, then tests how well those doses work when given alone or combined with other cancer drugs. All 429 participants will …

This study is testing an experimental immunotherapy drug called AK104 for women with a rare, aggressive form of cervical cancer that has returned or spread after prior chemotherapy. The main goal is to see if the drug can keep the cancer from growing for at least 6 months. Resear…

This study is testing whether combining a precise, high-dose radiation treatment (SBRT) with an immunotherapy drug (atezolizumab) works better than the drug alone for cervical cancer that has returned or spread. It involves about 21 women with advanced cervical cancer. The goal i…

This study aimed to compare the standard Pap smear test to a new molecular blood test for detecting abnormal cervical cell changes. It planned to enroll women aged 18-85 to see if the blood test, which looks for specific protein markers, could be as good as or better than current…

This study is testing whether injecting a small amount of radioactive sugar (18F-FDG) into the cervix before a PET/CT scan can create a clearer picture of which lymph nodes contain cancer. Researchers want to see if this method helps surgeons better identify and remove cancerous …

This study is testing a new, non-invasive method to detect persistent viruses in people with cervical cancer. Researchers will use a special device to measure tiny electrical signals at acupuncture points on the skin, looking for patterns linked to viruses like HPV and COVID-19. …

This study is testing different screening methods to find the best way to detect cervical cancer early in Botswana, especially for women living with HIV. Researchers will compare HPV testing followed by visual exams to see which approach works best. The study also looks at costs …

This study is testing whether a peer support program can encourage more women in Uganda to get screened for cervical cancer. Women who have recently been screened will be trained to advocate for screening within their social circles. The goal is to see if this approach leads more…

This study is testing a web-based tracking system designed to help more women in Kenya get screened for cervical cancer and receive proper follow-up care if needed. It involves 10 hospitals and aims to see if the system improves how often women complete screening and get the righ…

This study is testing whether offering a free, at-home self-sampling kit helps more women get screened for cervical cancer. It focuses on women aged 31-64 in Belgium who haven't had a screening test in over 6 years. Researchers are comparing the kit's effectiveness when offered d…

This study is testing if mailing a simple, at-home HPV test kit can help more Asian and Asian American women get screened for cervical cancer. It focuses on women in a safety-net healthcare system who are overdue for their regular screening. The goal is to see if this convenient,…

This study aims to find the best ways to get more women in Kenya screened for breast and cervical cancer. It will test different community support strategies, like education and help navigating the healthcare system, to see which ones work best. The goal is to help women catch ca…

This study tests a health education program designed for women who are leaving jail. The program aims to improve their knowledge and actions related to preventing cervical cancer, breast cancer, sexually transmitted diseases, and unintended pregnancy. Researchers are comparing th…

This study is testing a program to prevent cervical cancer in four countries. It checks if offering HPV testing and immediate treatment for early cell changes is practical and well-received within local health systems. The goal is to find the best way to roll out these life-savin…

This program aims to prevent cervical cancer in a region of Kenya by combining two proven strategies: screening adult women for high-risk HPV and vaccinating young girls against the virus. It involves 2,300 participants, including mothers and their daughters, to test a community-…

This study is testing an online program called 'Journey Ahead' designed to help women with gynecologic cancers (like ovarian, cervical, or uterine cancer) develop better coping and communication skills. The program aims to reduce distress, improve emotional acceptance, and enhanc…

This study is testing whether a special program combining physiotherapy, yoga, and patient education can help reduce stress and pain for women undergoing a specific radiation treatment (brachytherapy) for cervical cancer. The treatment requires strict bed rest in isolation, which…

This study aims to understand the challenges transgender men face in accessing cervical cancer screening in France. Researchers are surveying 300 transgender men aged 25-65 who still have a cervix to identify barriers like discrimination, lack of provider knowledge, and administr…

This study aims to learn more about how brain and cervical cancers work by using two types of advanced scans (PET and MRI) together. Researchers want to see how oxygen levels and blood flow inside these tumors relate to each other and to features seen under a microscope. The stud…

This study aimed to test a smartphone app for patients with recurrent head, neck, or gynecologic cancers. The goal was to see if the app was easy to use and helpful for patients to report their daily symptoms, quality of life, and any barriers to their care during treatment. The …

This study is screening cancer patients to collect genetic information from their tumors and saliva. Researchers will analyze this data to identify patients who might qualify for future clinical trials testing new cellular therapies. No treatment is provided in this study—it's pu…

This study aims to understand if women with HIV and cervical cancer complete their cancer treatment at the same rate and experience the same side effects as women without HIV. It will follow 180 women in India who are receiving standard chemoradiation for cervical cancer. The goa…