New drug duo aims to wake up immune system against hard-to-treat cancers
NCT ID NCT05082259
First seen Feb 14, 2026 · Last updated May 16, 2026 · Updated 10 times
Summary
This early-phase trial tests a new drug, ASTX660, combined with the immunotherapy pembrolizumab in people with advanced solid tumours, including cervical and triple-negative breast cancer. The goal is to see if blocking certain proteins can make cancer cells die in a way that triggers a stronger immune attack. About 61 participants will take part to find the safest dose and check for early signs of tumour shrinkage.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CERVICAL CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Cambridge University Hospitals NHS Trust
RECRUITINGCambridge, CB2 0QQ, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
The Royal Marden NHS Foundation Trust - Drug Development Unit
RECRUITINGSutton, SM2 5PT, United Kingdom
Contact Phone: •••-•••-••••
-
The Royal Marsden NHS Foundation Trust - Breast Unit
RECRUITINGSutton, SM2 5PT, United Kingdom
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.