Experimental pill plus keytruda takes on tough cancers

NCT ID NCT05438420

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental oral drug called Q702 combined with the immunotherapy pembrolizumab (Keytruda) in people with advanced esophageal, stomach, liver, or cervical cancer that has worsened after prior treatment. The goal is to see if the combination is safe and can shrink tumors. About 120 participants will take Q702 daily in cycles and receive pembrolizumab by IV every three weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Q702 (an experimental oral drug) and pembrolizumab (an immunotherapy, brand name Keytruda)

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced cancers that have stopped responding to standard immunotherapy.

What could go wrong

This is an early-phase trial with only 120 participants, so results may not apply to everyone. The combination may cause significant side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical cancer esophageal cancer Esophageal Neoplasms gastric cancer gastric neoplasm hepatocellular carcinoma Liver Neoplasms pediatric hepatocellular carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, South Korea

  • CHA Bundang Medical Center

    Seongnam-si, South Korea

  • Norton Cancer Institute

    Louisville, Kentucky, 40202, United States

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital

    Seoul, South Korea

  • University of Southern California

    Los Angeles, California, 90033, United States