Experimental pill plus keytruda takes on tough cancers
NCT ID NCT05438420
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an experimental oral drug called Q702 combined with the immunotherapy pembrolizumab (Keytruda) in people with advanced esophageal, stomach, liver, or cervical cancer that has worsened after prior treatment. The goal is to see if the combination is safe and can shrink tumors. About 120 participants will take Q702 daily in cycles and receive pembrolizumab by IV every three weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Q702 (an experimental oral drug) and pembrolizumab (an immunotherapy, brand name Keytruda)
- What this could lead to
- If successful, this combination could offer a new treatment option for people with advanced cancers that have stopped responding to standard immunotherapy.
- What could go wrong
- This is an early-phase trial with only 120 participants, so results may not apply to everyone. The combination may cause significant side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asan Medical Center
Seoul, South Korea
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CHA Bundang Medical Center
Seongnam-si, South Korea
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Norton Cancer Institute
Louisville, Kentucky, 40202, United States
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Samsung Medical Center
Seoul, South Korea
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Seoul National University Hospital
Seoul, South Korea
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Severance Hospital
Seoul, South Korea
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University of Southern California
Los Angeles, California, 90033, United States
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Other studies related to the condition(s) this trial covers.
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- Can an antiviral make radiation more effective against cervical cancer?
- A high-tech camera may take the guesswork out of spotting a dangerous surgery complication
- Blood test score may flag High-Risk esophageal surgery patients