HEPATOCELLULAR CANCER

This early-phase study is testing the safety of a new personalized treatment for advanced cancers, primarily liver cancer. Doctors take a patient's own immune cells, modify them in a lab to better target cancer, and infuse them back. The main goal is to see if this approach is sa…

This is the first study in people testing an experimental drug called ABBV-324 for advanced liver cancer or a type of lung cancer. The main goals are to find a safe dose, see how the body processes the drug, and check if it helps shrink tumors. The study will enroll about 232 adu…

This study is testing a new oral medication called Alintegimod, given alongside the immunotherapy drugs ipilimumab and nivolumab. It aims to see if this combination is safe and can help control advanced cancers that have spread or returned after other treatments. The study will e…

This study is testing a new drug called PF-08634404 to see if it is safe and effective for treating advanced liver cancer that cannot be removed by surgery. It will be given alone or combined with another drug (ipilimumab) to 138 adults who have not had other whole-body treatment…

This study is testing a personalized vaccine designed to prevent liver cancer from coming back after surgery. The vaccine is custom-made for each patient using their own tumor and immune cells, and is given alongside an immunotherapy drug called nivolumab. The goal is to see if t…

This early-stage study is testing whether adding targeted radiation to two immunotherapy drugs is safe and tolerable for people with operable liver cancer. The goal is to shrink tumors before surgery to improve outcomes. About 20 participants will receive either the two drugs alo…

This study aims to learn if finding cancer cells or cancer DNA in a person's blood, urine, or bone marrow can help doctors better understand how cancer spreads. Researchers will collect samples from 100 people with cancer and 200 people at high risk for lung cancer to see if thes…