Engineered immune cells target hard-to-treat cancers in early trial

NCT ID NCT05003895

First seen Feb 05, 2026 · Last updated Jun 16, 2026 · Updated 21 times

Summary

This early-phase study tests a new treatment where a person's own immune cells are modified in a lab to better recognize and attack cancer cells that have a specific marker called GPC3. The main goal is to see if this therapy is safe for adults with advanced liver cancer or other solid tumors that have not responded to standard treatments. Participants receive chemotherapy followed by the modified cells and are monitored closely for side effects and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.