Engineered immune cells take on hard-to-treat cancers in early trial

NCT ID NCT05003895

First seen Feb 05, 2026 · Last updated Apr 29, 2026 · Updated 15 times

Summary

This early-phase study tests a personalized treatment where a patient's own immune cells are modified in a lab to better recognize and attack cancer cells that have a specific marker called GPC3. The study includes adults with advanced liver cancer or other solid tumors that express GPC3 and have not responded to prior treatment. The main goal is to check the safety of this approach and see if it is feasible to deliver the modified cells.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.