Keytruda takes on 15 advanced cancers in major trial

NCT ID NCT02628067

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2 trial tests the immunotherapy drug pembrolizumab (Keytruda) in people with 15 types of advanced solid tumors that have worsened after standard treatments. About 1,600 participants receive the drug to see if their tumors shrink or stop growing. The study also looks for biological markers that might predict who benefits most.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pembrolizumab (Keytruda)

What this could lead to

If successful, this could show that pembrolizumab helps shrink or control certain advanced cancers that have not responded to other treatments.

What could go wrong

This is an early-phase trial with no control group, so results may not confirm real benefit. Not all cancer types may respond, and side effects like immune-related inflammation can occur.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

anal carcinoma anal squamous cell carcinoma anus neoplasm autosomal dominant Parkinson disease 4 bile duct adenocarcinoma bile duct cancer bile duct neoplasm biliary tract cancer Biliary Tract Neoplasms cancer carcinoid tumor cervical cancer cervical carcinoma cervical squamous cell carcinoma cholangiocarcinoma colorectal carcinoma colorectal neoplasm endometrial cancer endometrial carcinoma endometrium neoplasm mesothelioma Microsatellite Instability neoplasm neuroendocrine neoplasm parotid gland cancer salivary gland cancer salivary gland carcinoma small cell lung carcinoma thyroid cancer thyroid gland carcinoma Thyroid Neoplasms Uterine Cervical Neoplasms vulva cancer vulvar carcinoma vulvar squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.