Keytruda takes on 15 advanced cancers in major trial

NCT ID NCT02628067

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This phase 2 trial tests the immunotherapy drug pembrolizumab (Keytruda) in people with 15 types of advanced solid tumors that have worsened after standard treatments. About 1,600 participants receive the drug to see if their tumors shrink or stop growing. The study also looks for biological markers that might predict who benefits most.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
pembrolizumab (Keytruda)
What this could lead to
If successful, this could show that pembrolizumab helps shrink or control certain advanced cancers that have not responded to other treatments.
What could go wrong
This is an early-phase trial with no control group, so results may not confirm real benefit. Not all cancer types may respond, and side effects like immune-related inflammation can occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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