ENDOMETRIAL CARCINOMA

This early-stage study is testing FT836, a new type of 'off-the-shelf' CAR T-cell therapy, in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how well the body tolerates FT836, which is given al…

This early-stage trial is testing a new drug called FOG-001 for people with advanced or spreading cancers that have specific genetic mutations. Researchers want to find the safest dose and see if the drug can shrink tumors or slow cancer growth. The study will include 575 partici…

This study is testing whether a much shorter, one-week course of targeted pelvic radiation, given alongside standard chemotherapy drugs, is practical for patients to complete. It aims to see if this combined approach is manageable for people with stage III endometrial cancer who …

This study is testing a new drug called tegavivint in children, teens, and young adults whose solid tumors or lymphomas have come back or haven't responded to other treatments. The main goals are to find the safest dose, understand the side effects, and see if the drug can help s…

This early-stage study is testing a new combination of two oral drugs, M1774 and ZEN-3694, for women with recurrent ovarian or endometrial cancer. The main goals are to find the safest and most effective dose and to see how well the drugs work together to stop cancer cell growth.…

This study is testing whether a personalized exercise program, guided by a Fitbit, helps patients with ovarian or endometrial cancer meet the recommended 150 minutes of weekly activity better than standard advice. It aims to see if more exercise improves quality of life, physical…

This study is testing a four-part treatment for advanced endometrial cancer that has come back or worsened after prior therapy. It combines a personalized vaccine made from a patient's own blood cells with three drugs designed to help the immune system attack the cancer. The goal…

This study is testing if adding newer, faster-to-administer targeted drugs to standard chemotherapy works better for people with a specific type of advanced uterine cancer (HER2-positive). It will involve 360 participants who have not had prior chemotherapy. The main goal is to s…

This study is testing new AI-powered image processing techniques to see if they can make MRI scans for pelvic cancers faster and produce clearer pictures. It will involve 60 adults who are already scheduled for scans to check for prostate or endometrial cancer. The goal is to see…

This study is testing whether cancer patients prefer to receive their standard drug treatments at home instead of in a clinic. Researchers want to see if home-based care reduces the burden of travel and improves treatment satisfaction and quality of life for patients. A specializ…

This study compares two types of radiation therapy given after surgery for cervical or endometrial cancer to see which causes fewer short-term side effects. Researchers want to know if proton radiation causes less bowel and bladder irritation than standard intensity-modulated rad…

This study aims to understand why high-risk endometrial cancer comes back after treatment. Researchers will collect blood and tissue samples from 100 patients to analyze their cancer's genetic makeup. The goal is to identify genetic patterns that might help predict recurrence and…