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New hope for advanced cancer: experimental drug CR-001 enters human trials

NCT ID NCT07335497

Recruiting now Disease control Sponsor: Crescent Biopharma, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 9 times

Summary

This study tests a new drug called CR-001 in adults with advanced solid tumors that have spread. The goal is to find the safest dose and see if it can shrink tumors. About 290 people will take part in this early-phase trial.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer cervical cancer colorectal cancer endometrial carcinoma gastroesophageal cancer hepatocellular carcinoma metastatic malignant neoplasm metastatic neoplasm Neoplasm Metastasis non-small cell lung carcinoma ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED / METASTATIC SOLID TUMORS

Contacts and locations

Locations

  • Clinical Study Site

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • Clinical Study Site

    RECRUITING

    Los Angeles, California, 90033, United States

  • Clinical Study Site

    RECRUITING

    Denver, Colorado, 80218, United States

  • Clinical Study Site

    RECRUITING

    Orlando, Florida, 32827, United States

  • Clinical Study Site

    RECRUITING

    Sarasota, Florida, 34236, United States

  • Clinical Study Site

    RECRUITING

    Detroit, Michigan, 48201, United States

  • Clinical Study Site

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • Clinical Study Site

    RECRUITING

    New York, New York, 10029, United States

  • Clinical Study Site

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Clinical Study Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Clinical Study Site

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Clinical Study Site

    RECRUITING

    Dallas, Texas, 75230, United States

  • Clinical Study Site

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Clinical Study Site

    RECRUITING

    West Valley City, Utah, 84119, United States

  • Clinical Study Site

    ACTIVE_NOT_RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Clinical Study Site

    RECRUITING

    Dublin, Ireland, Ireland

  • Clinical Study Site

    RECRUITING

    Milan, Milano, 20089, Italy

  • Clinical Study Site

    RECRUITING

    Candiolo, Torino, 10060, Italy

  • Clinical Study Site

    RECRUITING

    Cluj-Napoca, Cluj, 400015, Romania

  • Clinical Study Site

    RECRUITING

    Bucharest, 022328, Romania

  • Clinical Study Site

    RECRUITING

    Seoul, Seoul, 03080, South Korea

  • Clinical Study Site

    RECRUITING

    Seoul, Seoul, 03722, South Korea

  • Clinical Study Site

    RECRUITING

    Seoul, Seoul, 06351, South Korea

  • Clinical Study Site

    RECRUITING

    Seongnam-si, 13620, South Korea

  • Clinical Study Site

    RECRUITING

    Barcelona, Barcelona, 08023, Spain

  • Clinical Study Site

    RECRUITING

    Logroño, La Rioja, 26006, Spain

  • Clinical Study Site

    RECRUITING

    Madrid, Madrid, 28040, Spain

  • Clinical Study Site

    RECRUITING

    Madrid, Madrid, 28223, Spain

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