New drug HWK-007 targets Hard-to-Treat cancers in early trial

NCT ID NCT07444814

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called HWK-007 in people with advanced solid tumors, including certain ovarian, endometrial, and lung cancers. The drug is designed to target a protein (PTK7) found on cancer cells and deliver a chemotherapy-like payload directly to them. The main goals are to find the safest dose and check for side effects. About 226 adults will take part, and the study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm lung neoplasm non-small cell lung carcinoma ovarian cancer ovarian carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutchinson Cancer Center

    NOT_YET_RECRUITING

    Seattle, Washington, 98109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hackensack University Medical Center - John Theurer Cancer Center

    NOT_YET_RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT - Oncology - Houston

    RECRUITING

    Houston, Texas, 77054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NEXT Oncology - Austin

    RECRUITING

    Austin, Texas, 78758, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology - Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Roswell Park Comprehensive Care Center

    NOT_YET_RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • START - Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START - San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Francis Medical Center (OSF Healthcare)

    NOT_YET_RECRUITING

    Peoria, Illinois, 61637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA - Hematology/Oncology Clinical Research Unit

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital - Cleveland Medical Center

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Arkansas

    NOT_YET_RECRUITING

    Little Rock, Arkansas, 72205-7199, United States

    Contact Email: •••••@•••••

    Contact