One-Week radiation plus chemo for endometrial cancer: a feasibility trial
NCT ID NCT05691010
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests whether a short course of radiation (1 week instead of the usual 5) combined with standard chemotherapy (carboplatin and paclitaxel) is practical for people with stage III endometrial cancer. The trial will enroll 28 participants and aims to see if most can complete all 6 cycles of chemo without delays. It is a feasibility study, not designed to measure how well the treatment works against the cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- carboplatin and paclitaxel chemotherapy plus intensity-modulated radiation therapy (IMRT)
- What this could lead to
- If successful, this could lead to a shorter, more convenient treatment schedule for stage III endometrial cancer, reducing radiation from 5 weeks to 1 week.
- What could go wrong
- This is a very early feasibility study with only 28 participants. It is not designed to prove effectiveness, and the treatment may still cause significant side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Basking Ridge (All protocol activities)
RECRUITINGBasking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (All protocol activities)
RECRUITINGMontvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Memorial Sloan Kettering Commack (All protocol activities)
RECRUITINGCommack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (All protocol activities)
RECRUITINGMiddletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (All protocol activities)
RECRUITINGUniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (All protocol activities)
RECRUITINGHarrison, New York, 10604, United States
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