New drug BNT329 targets Hard-to-Treat cancers in early trial

NCT ID NCT07186842

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests a new drug called BNT329 in people with advanced solid tumors that have a specific marker (CA19-9). The main goals are to check safety and find the best dose. About 245 participants will take part. The drug works by targeting cancer cells and may help control tumor growth, but it is not expected to be a cure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Austin Health

    RECRUITING

    Heidelberg, 3084, Australia

  • Florida Cancer Specialists

    RECRUITING

    Orlando, Florida, 32827, United States

  • Hospital San Pedro

    RECRUITING

    Logroño, 26006, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario HM Sanchinarro - START Madrid CIOCC

    RECRUITING

    Madrid, 28050, Spain

  • Hospital Universitario Quironsalud Madrid - NEXT Oncology

    RECRUITING

    Pozuelo de Alarcón, 28223, Spain

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Monash Health

    RECRUITING

    Clayton, 3168, Australia

  • Northern Centre for Cancer Research

    RECRUITING

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Royal Free Hospital

    RECRUITING

    London, NW3 2QG, United Kingdom

  • SCRI at HCA Health One

    RECRUITING

    Denver, Colorado, 80218, United States

  • St James´s University Hospital

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • St. Josef-Hospital im Katholischen Klinikum Bochum

    RECRUITING

    Bochum, 44791, Germany

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • The Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • Universitaetsklinikum Ulm

    RECRUITING

    Ulm, D-89081, Germany

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Other studies related to the condition(s) this trial covers.