SALIVARY GLAND CANCER

This study looks at how well the drug T-DXd works in adults with advanced HER2-positive solid tumors that have spread and are not responding to other treatments. About 100 people will be followed to see if their tumors shrink and how long that lasts. The goal is to provide a trea…

This study tests whether adding the targeted drug T-DM1 to standard chemoradiation can keep HER2-positive salivary gland cancer from returning. About 37 people with advanced but removable tumors will receive the drug after surgery. Researchers will track how many remain cancer-fr…

This study tests a drug called zanidatamab in people with advanced solid tumors that have high levels of HER2 protein. Participants must have already tried at least one other cancer treatment. The goal is to see if the drug can shrink tumors or stop them from growing. This is not…

This study is building a large registry of up to 13,600 adults with rare head and neck cancers across Europe. Researchers will collect information from existing databases and doctors to track how these cancers behave, what treatments work best, and how patients fare over time. No…

This study is testing a small implantable device that delivers tiny amounts of different drugs directly into head and neck tumors. The goal is to see which drugs kill cancer cells best in each person, without giving the full treatment yet. About 30 adults with certain head and ne…

This study is creating a large database of medical information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. The goal is to help researchers better understand what causes cancer, how it progresses, and how to improve p…